Academic Journal
Effect of cognitive-existential group therapy on survival in early-stage breast cancer
| العنوان: | Effect of cognitive-existential group therapy on survival in early-stage breast cancer |
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| المؤلفون: | Kissane, David, Love, Anthony, Hatton, Allison, Bloch, Sidney, Smith, Graeme, Clarke, David, Miach, Patricia, Ikin, Jillian, Ranieri, Nadia, Snyder, Raymond |
| بيانات النشر: | American Society of Clinical Oncology |
| سنة النشر: | 2004 |
| المجموعة: | Federation University Australia: FedUni ResearchOnline |
| مصطلحات موضوعية: | 1112 Oncology and Carcinogenesis |
| الوصف: | PURPOSE: Cognitive-existential group therapy (CEGT) was developed to improve mood and mental attitude toward cancer in women with early-stage breast cancer receiving adjuvant chemotherapy. Given the debate about group therapy's association with increased survival in women with metastatic breast cancer, we were curious to check its effect at a much earlier stage in the cancer journey. PATIENTS AND METHODS: We randomly assigned 303 women with early-stage breast cancer who were receiving adjuvant chemotherapy to either 20 sessions of weekly group therapy plus three relaxation classes (n = 154) or to a control condition of three relaxation classes alone (n = 149). The primary outcome was survival. RESULTS: CEGT did not extend survival; the median survival time was 81.9 months (95% CI, 64.8 to 99.0 months) in the group-therapy women and 85.5 months (95% CI, 67.5 to 103.6 months) in the control arm. The hazard ratio for death was 1.35 (95% CI, 0.76 to 2.39; P = .31). In contrast, histology and axillary lymph node status were significant predictors of survival. Low-grade histology yielded a hazard ratio of 0.342 (95% CI, 0.17 to 0.69), and axillary lymph node-negative status yielded a hazard ratio of 0.397 (95% CI, 0.20 to 0.78). CONCLUSION: CEGT does not prolong survival in women with early-stage breast cancer. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| Relation: | Journal of Clinical Oncology Vol. 22, no. 21 (2004), p. 4255-4260; http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/34803; vital:3153; https://doi.org/10.1200/jco.2004.12.129 |
| DOI: | 10.1200/jco.2004.12.129 |
| الاتاحة: | http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/34803 https://doi.org/10.1200/jco.2004.12.129 |
| Rights: | Copyright American Society of Clinical Oncology ; This metadata is freely available under a CCO license |
| رقم الانضمام: | edsbas.33AED8A8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1200/jco.2004.12.129 |
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