Academic Journal
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
| العنوان: | IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes |
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| المؤلفون: | Yukihide Momozawa, Julia Dmitrieva, Emilie Théâtre, Valérie Deffontaine, Souad Rahmouni, Benoît Charloteaux, François Crins, Elisa Docampo, Mahmoud Elansary, Ann-Stephan Gori, Christelle Lecut, Rob Mariman, Myriam Mni, Cécile Oury, Ilya Altukhov, Dmitry Alexeev, Yuri Aulchenko, Leila Amininejad, Gerd Bouma, Frank Hoentjen, Mark Löwenberg, Bas Oldenburg, Marieke J. Pierik, Andrea E. vander Meulen-de Jong, C. Janneke van der Woude, Marijn C. Visschedijk, The International IBD Genetics Consortium, Mark Lathrop, Jean-Pierre Hugot, Rinse K. Weersma, Martine De Vos, Denis Franchimont, Severine Vermeire, Michiaki Kubo, Edouard Louis, Michel Georges |
| المصدر: | Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
| بيانات النشر: | Nature Portfolio |
| سنة النشر: | 2018 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Science |
| الوصف: | Most of the more than 200 known genetic risk loci for inflammatory bowel disease (IBD) reside in regulatory regions. Here, the authors provide eQTL datasets for six circulating immune cell types and ileal, colonic and rectal biopsies to map regulatory modules and identify potential causative genes for IBD. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2041-1723 |
| Relation: | https://doi.org/10.1038/s41467-018-04365-8; https://doaj.org/toc/2041-1723; https://doaj.org/article/c3282316b00248958032424db0e3a0c7 |
| DOI: | 10.1038/s41467-018-04365-8 |
| الاتاحة: | https://doi.org/10.1038/s41467-018-04365-8 https://doaj.org/article/c3282316b00248958032424db0e3a0c7 |
| رقم الانضمام: | edsbas.3305DB7F |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20411723 |
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| DOI: | 10.1038/s41467-018-04365-8 |