Academic Journal
Easy-BILAG: a new tool for simplified recording of SLE disease activity using BILAG-2004 index
| العنوان: | Easy-BILAG: a new tool for simplified recording of SLE disease activity using BILAG-2004 index |
|---|---|
| المؤلفون: | Carter, Lucy M, Gordon, Caroline, Yee, Chee-Seng, Bruce, Ian, Isenberg, David, Skeoch, Sarah, Vital, Edward M |
| المصدر: | Rheumatology (2022) (In press). |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2022 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | BILAG, assessment, disease activity, index, systemic lupus erythematosus |
| الوصف: | OBJECTIVE: BILAG-2004 index is a comprehensive disease activity instrument for SLE but administrative burden and potential frequency of errors limits its use in routine practice. We aimed to develop a tool for more accurate, time-efficient scoring of BILAG-2004 index with full fidelity to the existing instrument. METHODS: Frequency of BILAG-2004 items was collated from a BILAG-biologics registry (BILAG-BR) dataset. Easy-BILAG prototypes were developed to address known issues affecting speed and accuracy. After expert verification, accuracy and usability of the finalized Easy-BILAG was validated against standard format BILAG-2004 in a workbook exercise of 10 case vignettes. Thirty-three professionals ranging in expertise from 14 UK centres completed the validation exercise. RESULTS: Easy-BILAG incorporates all items present in ≥5% BILAG-BR records, plus full constitutional and renal domains into a rapid single page assessment. An embedded glossary and colour-coding assists domain scoring. A second page captures rarer manifestations when needed. In the validation exercise, Easy-BILAG yielded higher median scoring accuracy (96.7%) than standard BILAG-2004 documentation (87.8%, P = 0.001), with better inter-rater agreement. Easy-BILAG was completed faster (59.5 min) than the standard format (80.0 min, P = 0.04) for 10 cases. An advantage in accuracy was observed with Easy-BILAG use among general hospital rheumatologists (91.3 vs 75.0, P = 0.02), leading to equivalent accuracy as tertiary centre rheumatologists. Clinicians rated Easy-BILAG as intuitive, convenient, and well adapted for routine practice. CONCLUSION: Easy-BILAG facilitates more rapid and accurate scoring of BILAG-2004 across all clinical settings, which could improve patient care and biologics prescribing. Easy-BILAG should be adopted wherever BILAG-2004 assessment is required. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10144122/1/Isenberg_keab883.pdf; https://discovery.ucl.ac.uk/id/eprint/10144122/ |
| الاتاحة: | https://discovery.ucl.ac.uk/id/eprint/10144122/1/Isenberg_keab883.pdf https://discovery.ucl.ac.uk/id/eprint/10144122/ |
| Rights: | open |
| رقم الانضمام: | edsbas.32993C00 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |