Academic Journal
Malnutrition and Fracture Healing:Are Specific Deficiencies in Amino Acids Important in Nonunion Development?
| العنوان: | Malnutrition and Fracture Healing:Are Specific Deficiencies in Amino Acids Important in Nonunion Development? |
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| المؤلفون: | Meesters, Dennis M., Wijnands, Karolina A. P., Brink, Peter R. G., Poeze, Martijn |
| المصدر: | Meesters , D M , Wijnands , K A P , Brink , P R G & Poeze , M 2018 , ' Malnutrition and Fracture Healing : Are Specific Deficiencies in Amino Acids Important in Nonunion Development? ' , Nutrients , vol. 10 , no. 11 , 1597 . https://doi.org/10.3390/nu10111597 |
| سنة النشر: | 2018 |
| المجموعة: | Maastricht University Research Publications |
| مصطلحات موضوعية: | fracture healing, nonunion, arginine, citrulline, nitric oxide, nitric oxide synthase, NITRIC-OXIDE SYNTHASE, BONE MORPHOGENETIC PROTEINS, L-ARGININE, RISK-FACTORS, COLLAGEN-SYNTHESIS, ELDERLY-PATIENTS, EXPRESSION, GROWTH, CLASSIFICATION, EPIDEMIOLOGY |
| الوصف: | With the increasing incidence of fractures now, and in the future, the absolute number of bone-healing complications such as nonunion development will also increase. Next to fracture-dependent factors such as large bone loss volumes and inadequate stabilization, the nutritional state of these patients is a major influential factor for the fracture repair process. In this review, we will focus on the influence of protein/amino acid malnutrition and its influence on fracture healing. Mainly, the arginine-citrulline-nitric oxide metabolism is of importance since it can affect fracture healing via several precursors of collagen formation, and through nitric oxide synthases it has influences on the bio-molecular inflammatory responses and the local capillary growth and circulation. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.3390/nu10111597 |
| الاتاحة: | https://cris.maastrichtuniversity.nl/en/publications/27ef8b16-925a-4024-8c40-679a088b6d30 https://doi.org/10.3390/nu10111597 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.324E5710 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/nu10111597 |
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