Academic Journal
Understanding Alzheimer's disease as a disorder of consciousness
| العنوان: | Understanding Alzheimer's disease as a disorder of consciousness |
|---|---|
| المؤلفون: | Huntley, JD, Fleming, SM, Mograbi, DC, Bor, D, Naci, L, Owen, AM, Howard, R |
| المصدر: | Alzheimer’s & Dementia: Translational Research & Clinical Interventions , 7 (1) , Article e12203. (2021) |
| سنة النشر: | 2021 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | Alzheimer's disease, awareness, consciousness |
| الوصف: | People with Alzheimer's disease (AD) demonstrate a range of alterations in consciousness. Changes in awareness of cognitive deficit, self-awareness, and introspection are seen early in AD, and dysfunction of awareness and arousal progresses with increasing disease severity. However, heterogeneity of deficits between individuals and a lack of empirical studies in people with severe dementia highlight the importance of identifying and applying biomarkers of awareness in AD. Impairments of awareness in AD are associated with neuropathology in regions that overlap with proposed neural correlates of consciousness. Recent developments in consciousness science provide theoretical frameworks and experimental approaches to help further understand the conscious experience of people with AD. Recognition of AD as a disorder of consciousness is overdue, and important to both understand the lived experience of people with AD and to improve care. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10140339/1/Howard_Understanding%20Alzheimer%27s%20disease%20as%20a%20disorder%20of%20consciousness_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10140339/ |
| الاتاحة: | https://discovery.ucl.ac.uk/id/eprint/10140339/1/Howard_Understanding%20Alzheimer%27s%20disease%20as%20a%20disorder%20of%20consciousness_VoR.pdf https://discovery.ucl.ac.uk/id/eprint/10140339/ |
| Rights: | open |
| رقم الانضمام: | edsbas.30B697F0 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |