Academic Journal
Extracardiac findings with increased perfusion during clinical O-15-H 2 O PET/CT myocardial perfusion imaging:a case series
| العنوان: | Extracardiac findings with increased perfusion during clinical O-15-H 2 O PET/CT myocardial perfusion imaging:a case series |
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| المؤلفون: | Jochumsen, Mads Ryø, Overgaard, David Lyse, Vendelbo, Mikkel, Madsen, Michael Alle, Tolbod, Lars Poulsen, Gormsen, Lars Christian, Ørhøj Barkholt, Trine |
| المصدر: | Jochumsen , M R , Overgaard , D L , Vendelbo , M , Madsen , M A , Tolbod , L P , Gormsen , L C & Ørhøj Barkholt , T 2023 , ' Extracardiac findings with increased perfusion during clinical O-15-H 2 O PET/CT myocardial perfusion imaging : a case series ' , Journal of Nuclear Cardiology , vol. 30 , no. 4 , pp. 1458-1468 . https://doi.org/10.1007/s12350-022-03156-5 |
| سنة النشر: | 2023 |
| المجموعة: | Aarhus University: Research |
| مصطلحات موضوعية: | O-15-H O PET, cardiac PET, coincidental findings, extra cardiac, myocardial perfusion, positron emission tomography, splenic switch off |
| الوصف: | Background: Coincidental extracardiac findings with increased perfusion were reported during myocardial perfusion imaging (MPI) with various retention radiotracers. Clinical parametric O-15-H2O PET MPI yielding quantitative measures of myocardial blood flow (MBF) was recently implemented at our facility. We aim to explore whether similar extracardiac findings are observed using O-15-H2O. Methods and results: All patients (2963) were scanned with O-15-H2O PET MPI according to international guidelines and extracardiac findings were collected. In contrast to parametric O-15-H2O MBF images, extracardiac perfusion was assessed using summed images. Biopsy histopathology and other imaging modalities served as reference standards. Various malignant lesions with increased perfusion were detected, including lymphomas, large-celled neuroendocrine tumour, breast, and lung cancer plus metastases from colonic and renal cell carcinomas. Furthermore, inflammatory and hyperplastic benign conditions with increased perfusion were observed: rib fractures, gynecomastia, atelectasis, sarcoidosis, pneumonia, chronic lung inflammation and fibrosis, benign lung nodule, chronic diffuse lung infiltrates, pleural plaques and COVID-19 infiltrates. Conclusions: Malignant and benign extracardiac coincidental findings with increased perfusion are readily visible and frequently seen on O-15-H2O PET MPI. We recommend evaluating the summed O-15-H2O PET images in addition to the low-dose CT attenuation images. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1007/s12350-022-03156-5 |
| الاتاحة: | https://pure.au.dk/portal/en/publications/a21349d0-2dd3-4674-a8ab-4b48fc6e121a https://doi.org/10.1007/s12350-022-03156-5 http://www.scopus.com/inward/record.url?scp=85145573679&partnerID=8YFLogxK https://rdcu.be/c2MWn |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2F966672 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s12350-022-03156-5 |
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