Academic Journal
All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals
| العنوان: | All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals |
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| المؤلفون: | Amelie C. F. Bergs, Jana F. Liewald, Silvia Rodriguez-Rozada, Qiang Liu, Christin Wirt, Artur Bessel, Nadja Zeitzschel, Hilal Durmaz, Adrianna Nozownik, Holger Dill, Maëlle Jospin, Johannes Vierock, Cornelia I. Bargmann, Peter Hegemann, J. Simon Wiegert, Alexander Gottschalk |
| المصدر: | Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023) |
| بيانات النشر: | Nature Portfolio |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Science |
| الوصف: | Optogenetic actuation regimes are often static, which allows perturbation, but not true control of neuronal activity. Here, the authors describe an all-optical method for bidirectional steering of membrane potential, in closed loop, in C. elegans muscles and neurons, and rat hippocampal slice culture. The ‘optogenetic voltage clamp’ uses two microbial rhodopsin actuators and the rhodopsin voltage indicator QuasAr. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2041-1723 |
| Relation: | https://doi.org/10.1038/s41467-023-37622-6; https://doaj.org/toc/2041-1723; https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6 |
| DOI: | 10.1038/s41467-023-37622-6 |
| الاتاحة: | https://doi.org/10.1038/s41467-023-37622-6 https://doaj.org/article/4373263f0a2a4c2cbd268fdc4a4ba5a6 |
| رقم الانضمام: | edsbas.2F72C3C6 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20411723 |
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| DOI: | 10.1038/s41467-023-37622-6 |