Academic Journal
Standardization of $^{68}$Ge/$^{68}$Ga using the 4$\pi \beta-\gamma$ coincidence method based on Cherenkov counting
| العنوان: | Standardization of $^{68}$Ge/$^{68}$Ga using the 4$\pi \beta-\gamma$ coincidence method based on Cherenkov counting |
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| المؤلفون: | Bobin, Christophe, Thiam, Cheick, Bouchard, Jacques |
| المساهمون: | Laboratoire National Henri Becquerel (CEA, LIST) (LNHB (CEA, LIST)), Département Métrologie Instrumentation & Information (CEA, LIST) (DM2I (CEA, LIST)), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay |
| المصدر: | ISSN: 0969-8043. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Cherenkov effect, PHOTOCATHODES, EXTRAPOLATION, Liquid scintillation, Geant4 modeling, metrology, radioactivity, ionizing radiation, beta-gamma coincidence counting, Radionuclide metrology, Primary activity measurement, modelling, simulation, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation |
| الوصف: | Proceeding of the 21st International Conference on Radionuclide Metrology and its Applications (ICRM), Argentinian Comis Nacl Energia Atomica, Buenos Aires, ARGENTINA, MAY 15-19, 2017. Organizer: Argentinian Comis Nacl Energia Atomica. ; International audience ; In the framework of an international BIPM comparison (Bureau International des Poids et Mesures), the activity standardization of $^{68}$Ge in a solution of $^{68}$Ge/$^{68}$Ga in equilibrium provided by NIST was carried out at LNHB. This exercise was organized to meet the growing interest in $^{68}$Ga as a radiopharmaceutical in nuclear medicine services (e.g. as a surrogate of $^{18}$F for PET imaging). Due to the volatility of germanium, the activity standardization of $^{68}$Ge was investigated at LNHB by means of 4$\pi \beta -\gamma$ coincidence counting based on Cherenkov measurements. This technique was applied to take advantage of the Cherenkov threshold (similar to 260 keV in aqueous solutions) in order to prevent counting from electron-capture events associated with $^{68}$Ge disintegrations. Cherenkov counting was performed using glass and polyethylene vials and the resulting activity concentrations were compared with 4$\pi \beta -\gamma$ coincidence measurements based on liquid scintillation. The efficiency-extrapolation curve obtained with Cherenkov measurements in glass vials was compared to Monte Carlo simulations based on the Geant4 code. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.apradiso.2017.06.044 |
| الاتاحة: | https://cea.hal.science/cea-01799861 https://cea.hal.science/cea-01799861v1/document https://cea.hal.science/cea-01799861v1/file/article_ChristopheBobin_Cheick%20Thiam_IRCM2017.pdf https://doi.org/10.1016/j.apradiso.2017.06.044 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.2F2B3DB1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.apradiso.2017.06.044 |
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