Academic Journal
Myocarditis mortality with and without COVID-19: insights from a national registry
| العنوان: | Myocarditis mortality with and without COVID-19: insights from a national registry |
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| المؤلفون: | Bemtgen, Xavier, Kaier, Klaus, Rilinger, Jonathan, Rottmann, Felix A., Supady, Alexander, Zur Mühlen, Constantin von, Westermann, Dirk, Wengenmayer, Tobias, Staudacher, Dawid |
| المصدر: | Clinical research in cardiology. - 113, 2 (2024) , 216-222, ISSN: 1861-0692 |
| سنة النشر: | 2024 |
| المجموعة: | University of Freiburg: FreiDok |
| الوصف: | Background Myocarditis in context of a SARS-CoV-2 infection is vividly discussed in the literature. Real-world data however are sparse, and relevance of the myocarditis diagnosis to outcome in coronavirus disease (COVID-19) is unclear. Patients and methods Retrospective analysis of 75,304 patients hospitalized in Germany with myocarditis between 2007 and 2020 is reported by DESTATIS. Patients hospitalized between 01/2016 and 12/2019 served as reference cohort for the COVID-19 patients hospitalized in 2020. Results A total of 75,304 patients were hospitalized between 2007 and 2020 (age 42.5 years, 30.1% female, hospital mortality 2.4%). In the reference cohort, 24,474 patients (age 42.8 years, 29.5% female, hospital mortality 2.2%) were registered. In 2020, annual myocarditis hospitalizations dropped by 19.6% compared to reference (4921 vs. 6119 annual hospitalization), of which 443/4921 (9.0%) were connected to COVID-19. In 2020, hospital mortality of myocarditis in non-COVID-19 patients increased significantly compared to reference (2.9% vs. 2.2%, p = 0.008, OR 1.31, 95% CI 1.08–1.60). In COVID-19 myocarditis, hospital mortality was even higher compared to reference (13.5% vs. 2.2%, p < 0.001, OR 6.93, 95% CI 5.18–9.18). Conclusion The burden of patients with myocarditis and COVID-19 in 2020 was low. Hospital mortality was more than sixfold higher in patients with myocarditis and COVID-19 compared to those with myocarditis but without COVID-19. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | |
| اللغة: | English |
| Relation: | https://freidok.uni-freiburg.de/data/232430 |
| DOI: | 10.1007/s00392-022-02141-9 |
| الاتاحة: | https://freidok.uni-freiburg.de/data/232430 https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-2324307 https://doi.org/10.1007/s00392-022-02141-9 https://freidok.uni-freiburg.de/dnb/download/232430 |
| Rights: | free |
| رقم الانضمام: | edsbas.2E521FA3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00392-022-02141-9 |
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