التفاصيل البيبلوغرافية
| العنوان: |
Bifunctional Urea/Hg(OAc) 2 ‑Mediated Synthesis of 4‑Aryl-6-oxycarbonyl-2-pyrones and 2‑Pyridones from Dithiomalonate and β,γ-Unsaturated α‑Keto Esters |
| المؤلفون: |
Daeil Bae (10525809), Juyeol Lee (3963200), Hui Jin (38113), Do Hyun Ryu (510974) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Ecology, Marine Biology, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, yield, 2- pyridones, Hg, one-pot two-stage protocol, α- keto esters, pyrone |
| الوصف: |
Disubstituted 2-pyrones and 2-pyridones were obtained by bifunctional urea-catalyzed Michael addition/lactonization or lactamization followed by a Hg(OAc) 2 - or Hg(OAc) 2 /DBU-mediated hydrolysis/decarboxylation/dehydrogenation process. This one-pot two-stage protocol enabled the rapid synthesis of 4,6-disubstituted 2-pyrones and 2-pyridones from dithiomalonate and β,γ-unsaturated α-keto esters in practical yields under mild reaction conditions. Additionally, the obtained 2-pyridones were facilely transformed to 2,4,6-trisubstituted pyridines in excellent yields. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Bifunctional_Urea_Hg_OAc_sub_2_sub_Mediated_Synthesis_of_4_Aryl-6-oxycarbonyl-2-pyrones_and_2_Pyridones_from_Dithiomalonate_and_-Unsaturated_Keto_Esters/14372106 |
| DOI: |
10.1021/acs.joc.1c00323.s001 |
| الاتاحة: |
https://doi.org/10.1021/acs.joc.1c00323.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.2E430F62 |
| قاعدة البيانات: |
BASE |