Academic Journal
Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy ; Молекулярно-генетический и биохимический профили злокачественных новообразований на фоне беременности
| العنوان: | Molecular genetic and biochemical profiles of malignant neoplasms during pregnancy ; Молекулярно-генетический и биохимический профили злокачественных новообразований на фоне беременности |
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| المؤلفون: | A. L. Chernyshova, A. A. Chernyakov, Yu. M. Truschuk, N. V. Yunusova, N. V. Sevostyanova, Ya. I. Arkhipova, O. S. Dil, A. E. Chernyshova, А. Л. Чернышова, А. А. Черняков, Ю. М. Трущук, Н. В. Юнусова, Н. В. Севостьянова, Я. И. Архипова, О. С. Диль, А. Е. Чернышова |
| المصدر: | Advances in Molecular Oncology; Том 11, № 3 (2024); 32-40 ; Успехи молекулярной онкологии; Том 11, № 3 (2024); 32-40 ; 2413-3787 ; 2313-805X |
| بيانات النشر: | “ABV-press” Publishing house”, LLC |
| سنة النشر: | 2024 |
| المجموعة: | Advances in molecular oncology (E-Journal) / Успехи молекулярной онкологии |
| مصطلحات موضوعية: | прогноз, pregnancy, placenta, molecular genetic factor, biochemical marker, prognosiss, беременность, плацента, молекулярно-генетический фактор, биохимический маркер |
| الوصف: | The article presents a review of modern literature data on molecular-genetic and biochemical profiles of malignant tumors of varying locations. It is shown that molecular-genetic and transcription profiles of pregnancy-associated malignant tumors are systems consisting of various components, many of which remain poorly researched. Additionally, morphological and biochemical characteristics of the placenta and tumor tissue are discussed. In the recent years, individual researchers and research groups have demonstrated heightened interests in this problem which undoubtedly soon will lead to a deeper and stronger understanding of mechanisms of progression and metastasis of oncological diseases during pregnancy. The knowledge of the principles of normal embryogenesis as a process of intrauterine development of a fetus, as well as investigation of molecular basis of pathogenesis of spontaneous abortion will undoubtedly help in determination of new targets and development of new therapeutical molecules for cancer treatment. ; В статье представлен обзор современных данных литературы о молекулярно-генетических и биохимических профилях злокачественных новообразований различных локализаций. Показано, что молекулярно-генетический и транскрипционный профили злокачественных опухолей, ассоциированных с беременностью, являются системами, включающими различные компоненты, многие из которых к настоящему моменту остаются малоизученными. Также рассмотрены морфологические и биохимические особенности плаценты и опухолевой ткани. В последние годы наблюдается повышенный интерес отдельных исследователей и групп ученых к данному вопросу, что, несомненно, в скором времени приведет к более глубокому и четкому пониманию механизмов метастазирования и прогрессирования онкологических заболеваний на фоне беременности. Знание закономерностей нормального эмбриогенеза как процесса внутриутробного развития зародыша в полости матки во время беременности, а также изучение молекулярных основ патогенеза состояний спонтанного прерывания беременности, ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
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| DOI: | 10.17650/2313-805X-2024-11-3-32-40 |
| الاتاحة: | https://umo.abvpress.ru/jour/article/view/706 https://doi.org/10.17650/2313-805X-2024-11-3-32-40 |
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| رقم الانضمام: | edsbas.2DB8EB30 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17650/2313-805X-2024-11-3-32-40 |
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