Academic Journal
A distinctive role for galectin-7 in cancer?
| العنوان: | A distinctive role for galectin-7 in cancer? |
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| المؤلفون: | St-Pierre, Yves, Campion, Carole G., Grosset, Andree-Anne |
| سنة النشر: | 2012 |
| المجموعة: | Institut national de la recherche scientifique, Québec: Espace INRS |
| مصطلحات موضوعية: | Galectins, Apoptosis, Mammary Cancer, Mammary Myoepithelial Cells, p53 |
| الوصف: | The galectins are a family of evolutionay-conserved carbohydrate-binding proteins. They are distributed widely in all living organisms and have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis. Several members of the galectin family have also been shown to be involved in cancer progression and metastasis. In the case of galectin-7, several studies have reported alterations in its expression pattern during cancer progression. In a variety of tumors, its expression can range from being completely down-regulated to highly up-regulated. Accordingly, its precise role in this field is still debated. The evidence shows tiiat galectin-7 may promote or inhibit cancer development. In this article, we review the data concerning expression and roles of galectin-7 in cancer and propose a comprehensive view of its contribution during cancer progression. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://espace.inrs.ca/id/eprint/14094/1/A%20distinctive%20role%20for%20galectin-7%20in%20cancer.pdf; St-Pierre, Yves ORCID logoorcid:0000-0002-1948-2041; Campion, Carole G. et Grosset, Andree-Anne (2012). A distinctive role for galectin-7 in cancer? Frontiers in Bioscience , vol. 17 , nº 2. pp. 438-450. DOI:10.2741/3937 . |
| DOI: | 10.2741/3937 |
| الاتاحة: | https://espace.inrs.ca/id/eprint/14094/ https://espace.inrs.ca/id/eprint/14094/1/A%20distinctive%20role%20for%20galectin-7%20in%20cancer.pdf https://doi.org/10.2741/3937 |
| Rights: | cc_by_4 |
| رقم الانضمام: | edsbas.2D166CCF |
| قاعدة البيانات: | BASE |
| DOI: | 10.2741/3937 |
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