Academic Journal

Global sensitivity analysis–VEGFR1 following perturbations.

التفاصيل البيبلوغرافية
العنوان: Global sensitivity analysis–VEGFR1 following perturbations.
المؤلفون: Sarvenaz Sarabipour, Karina Kinghorn, Kaitlyn M. Quigley, Anita Kovacs-Kasa, Brian H. Annex, Victoria L. Bautch, Feilim Mac Gabhann
سنة النشر: 2024
مصطلحات موضوعية: Cell Biology, Immunology, Developmental Biology, Cancer, Infectious Diseases, subcellularly localized phosphatases, provides mechanistic insight, blood vessel growth, see &# 8217, cells &# 8212, understand vegfr activity, computational model describing, receptors alters competition, intracellular trafficking processes, regulates receptor activation, &# 8217, receptor alters, intracellular locations, endothelial cells, receptor network, %22">xlink ">, trafficking dynamics, simultaneously quantify, signaling complexes, low percentage, local levels, key drivers, human ecs, high levels, function differently
الوصف: This panel shows how changing the various trafficking and production parameters impacts the simulation predictions to be compared two key experimental data points: the change in whole cell VEGFR1 two hours after CHX administration ( A ) and the change in whole cell VEGFR1 18 hours after administration of siRNA against Rab4a and Rab11a ( B ). (PDF)
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
Relation: https://figshare.com/articles/journal_contribution/Global_sensitivity_analysis_VEGFR1_following_perturbations_/25171971
DOI: 10.1371/journal.pcbi.1011798.s016
الاتاحة: https://doi.org/10.1371/journal.pcbi.1011798.s016
https://figshare.com/articles/journal_contribution/Global_sensitivity_analysis_VEGFR1_following_perturbations_/25171971
Rights: CC BY 4.0
رقم الانضمام: edsbas.2CAA7B4E
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pcbi.1011798.s016