Academic Journal
Four-class drug-resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir-based antiretroviral therapy in Botswana.
| العنوان: | Four-class drug-resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir-based antiretroviral therapy in Botswana. |
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| المؤلفون: | Seatla, Kaelo K, Avalos, Ava, Moyo, Sikhulile, Mine, Madisa, Diphoko, Thabo, Mosepele, Mosepele, Gaolatlhe, Tendani, Rowley, Christopher F, Ramaabya, Dinah, Jarvis, Joseph N, Kasvosve, Ishmael, Gaseitsiwe, Simani |
| بيانات النشر: | Lippincott, Williams & Wilkins |
| سنة النشر: | 2018 |
| المجموعة: | London School of Hygiene & Tropical Medicine: LSHTM Research Online |
| الوصف: | There are limited data on the effectiveness of dolutegravir (DTG)-based combination antiretroviral therapy (ART) in real-life settings in southern Africa where HIV-1 subtype C predominates. We report a patient infected with HIV-1 subtype C on DTG-based ART previously exposed to raltegravir who developed multidrug resistance mutations to four antiretroviral classes. There is need for drug resistance monitoring and clinical vigilance to ensure effectiveness of HIV treatment programs even in the era of DTG-based ART. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://researchonline.lshtm.ac.uk/id/eprint/4648180/1/Four%20class%20drug%20resistant%20HIV_GREEN%20AAM.pdf; Seatla, Kaelo K; Avalos, Ava; Moyo, Sikhulile; Mine, Madisa; Diphoko, Thabo; Mosepele, Mosepele; Gaolatlhe, Tendani; Rowley, Christopher F; Ramaabya, Dinah; Jarvis, Joseph N ; +2 more. Kasvosve, Ishmael; Gaseitsiwe, Simani; (2018) Four-class drug-resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir-based antiretroviral therapy in Botswana. AIDS (London, England), 32 (13). pp. 1899-1902. ISSN 0269-9370 DOI: https://doi.org/10.1097/QAD.0000000000001920 |
| الاتاحة: | https://researchonline.lshtm.ac.uk/id/eprint/4648180/ https://researchonline.lshtm.ac.uk/id/eprint/4648180/1/Four%20class%20drug%20resistant%20HIV_GREEN%20AAM.pdf |
| Rights: | cc_by_nc_nd |
| رقم الانضمام: | edsbas.2C201B4 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |