Academic Journal
Pancreatitis crónica: análisis de factores de progresión de la enfermedad ; Chronic pancreatitis: analysis of disease progression factors
| العنوان: | Pancreatitis crónica: análisis de factores de progresión de la enfermedad ; Chronic pancreatitis: analysis of disease progression factors |
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| المؤلفون: | Diéguez Castillo, Carmelo, Jiménez Luna, Cristina, Prados Salazar, José Carlos, Caba Pérez, Octavio |
| بيانات النشر: | Sociedad Medica de Santiago de Chile |
| سنة النشر: | 2022 |
| المجموعة: | DIGIBUG: Repositorio Institucional de la Universidad de Granada |
| مصطلحات موضوعية: | Alcohol Drinking, Pancreatitis, Chronic, Tobacco |
| الوصف: | Background: Alcohol and tobacco are important risk factors for chronic pancreatitis (CP). Aim: To analyze the effect of etiological factors such as tobacco and alcohol and pancreatic enzyme replacement therapy (PERT) in the progression of CP. Material and Methods: Patients with a diagnosis of CP were recruited and grouped according to variables such as tobacco, alcohol and PERT. They were followed for 18 months. Subsequently, different variables and analytical parameters involved in the progression of the disease were analyzed. Results: A total of 50 patients diagnosed with CP were included. Of these, 28 patients underwent PERT, 39 were smokers and 33 were alcohol users. Compared with patients without PERT, those with PERT had a higher proportion of diabetes (64 and 32%, respectively), had a higher need for endoscopic treatment (25 and 0%, respectively) and a normal body mass index (71 and 27.3%, respectively. The smokers had higher calcium levels and increased lymphocytosis and leukocytosis. The alcohol consumption group had a higher mean age (p = 0.04) Conclusions: PERT may improve the nutritional status but does not reduce the need for endoscopic or surgical treatment. Smoking and alcohol consumption favored the progression of CP. Also, smoking induced a pro-inflammatory state. ; Fondos FEDER, A-CTS-436-UGR20 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Spanish; Castilian |
| Relation: | C. Diéguez et al. Pancreatitis crónica: análisis de factores de progresión de la enfermedad. Rev Med Chile 2022; 150: 1555-1564. [http://dx.doi.org/10.4067/s0034-98872022001201555]; https://hdl.handle.net/10481/84819 |
| DOI: | 10.4067/s0034-98872022001201555 |
| الاتاحة: | https://hdl.handle.net/10481/84819 https://doi.org/10.4067/s0034-98872022001201555 |
| Rights: | Atribución 4.0 Internacional ; http://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2C05C3EF |
| قاعدة البيانات: | BASE |
| DOI: | 10.4067/s0034-98872022001201555 |
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