Academic Journal
Myocardial Function Maturation in Very-Low-Birth-Weight Infants and Development of Bronchopulmonary Dysplasia
| العنوان: | Myocardial Function Maturation in Very-Low-Birth-Weight Infants and Development of Bronchopulmonary Dysplasia |
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| المؤلفون: | Méndez Abad, Paula, Zafra Rodríguez, Pamela, Lubián López, Simón Pedro, Benavente Fernández, Isabel |
| المساهمون: | Materno-Infantil y Radiología |
| المصدر: | Frontiers in Pediatrics - 2020, Volume 7, Article 556 |
| بيانات النشر: | FRONTIERS MEDIA SA |
| سنة النشر: | 2020 |
| المجموعة: | RODIN - Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz |
| مصطلحات موضوعية: | bronchopulmonary dysplasia, preterm infants, myocardial function, N-terminal pro B type natriuretic peptide, tissue doppler imaging, targeted neonatal echocardiography, biomarkers, tricuspid annular plane systolic excursion |
| الوصف: | Background: Myocardial function in very-low-birth-weight infants (VLBWIs) develops during early postnatal life, but different patterns of temporal evolution that might be related to the development of bronchopulmonary dysplasia (BPD) are not completely understood. Methods: A prospective cohort study including VLBWIs admitted to our NICU from January 2015 to 2017 was conducted. Plasma N-terminal pro B type natriuretic peptide (NTproBNP) levels were measured, and echocardiograms were performed at 24 and 72 h of life and weekly thereafter until 36 weeks of postmenstrual age (PMA). We measured the tricuspid annular plane systolic excursion (TAPSE) by M-mode; the lateral tricuspid E', A', and S' waves; and the myocardial performance index (MPI) by tissue doppler imaging (TDI). The subjects were divided into non-BPD and BPD groups. Results: We included 101 VLBWIs. The TAPSE and E', A', and S' waves increased while MPI-TDI decreased over time. Birth gestational age (GA) and postnatal PMA impacted these parameters, which evolved differently in those who developed BPD compared to those in the non-BPD group. The NTproBNP levels at 14 days of life and different echocardiographic parameters were associated with the development of BPD in different multivariate models. Conclusion: TAPSE and TDI values depend on GA and PMA and follow a different temporal evolution that is related to the later development of BPD. Combined biochemical and echocardiographic biomarkers can help identify which VLBWIs are at higher risk of developing BDP. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2296-2360 |
| Relation: | http://hdl.handle.net/10498/22355 |
| DOI: | 10.3389/fped.2019.00556 |
| الاتاحة: | http://hdl.handle.net/10498/22355 https://doi.org/10.3389/fped.2019.00556 |
| Rights: | Atribución 4.0 Internacional ; http://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2A2E3FA6 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 22962360 |
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| DOI: | 10.3389/fped.2019.00556 |