Academic Journal

Liver enzymes and blood metabolites in a population of free-ranging red deer ( Cervus elaphus) naturally infected with Fascioloides magna

التفاصيل البيبلوغرافية
العنوان: Liver enzymes and blood metabolites in a population of free-ranging red deer ( Cervus elaphus) naturally infected with Fascioloides magna
المؤلفون: Severin, K., Mašek, T., Janicki, Z., Konjević, D., Slavica, A., Marinculić, A., Martinković, F., Vengušt, G., Džaja, P.
المصدر: Journal of Helminthology ; volume 86, issue 2, page 190-196 ; ISSN 0022-149X 1475-2697
بيانات النشر: Cambridge University Press (CUP)
سنة النشر: 2011
الوصف: We investigated the effects of Fascioloides magna infection on the serum biochemistry values of the naturally infected red deer population in eastern Croatia. The investigation was performed on 47 red deer with F. magna infection confirmed patho-anatomically in 27 animals (57.4%). Fibrous capsules and migratory lesions were found in 14 deer while only fibrous capsules without migratory lesions were found in 13 deer. In 13 deer both immature and mature flukes were found, in 5 deer only immature flukes were found and in 9 deer only mature flukes were found. Fascioloides magna infected deer with fibrous capsules and migratory lesions had significantly higher values for lactate dehydrogenase (LDH), glutamate dehydrogenase (GLDH) and globulin, and lower values for albumin/globulin ratio and glucose compared to uninfected deer. Fascioloides magna infected deer with fibrous capsules without the presence of migratory lesions had higher values for alanine aminotransferase (ALT) and globulin, and lower values for albumin/globulin ratio and glucose, than the uninfected deer. The number of immature flukes was positively correlated with values of aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), LDH, GLDH, urea and triglycerides. The number of migratory lesions was positively correlated with GGT, GLDH, globulin and urea values. The creatinine value was positively correlated with the number of mature flukes. The trial showed that F. magna infection causes significant changes in serum biochemistry. Moreover, these changes do not completely resemble changes following F. hepatica infection. Further investigation of changes in liver enzymes and other serum metabolites in controlled, experimentally induced fascioloidosis in red deer is needed to better understand the pathogenesis of F. magna .
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1017/s0022149x1100023x
الاتاحة: http://dx.doi.org/10.1017/s0022149x1100023x
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0022149X1100023X
Rights: https://www.cambridge.org/core/terms
رقم الانضمام: edsbas.2A14174A
قاعدة البيانات: BASE
الوصف
DOI:10.1017/s0022149x1100023x