Academic Journal
Comparative study on the degradation of cephalexin by four electrochemical advanced oxidation processes: Evolution of oxidation intermediates and antimicrobial activity
| العنوان: | Comparative study on the degradation of cephalexin by four electrochemical advanced oxidation processes: Evolution of oxidation intermediates and antimicrobial activity |
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| المؤلفون: | Antonin, Vanessa S., Aquino, Jose M., Silva, Bianca F., Silva, Adilson J., Rocha-Filho, Romeu C. |
| المساهمون: | Universidade Estadual Paulista (UNESP) |
| بيانات النشر: | Elsevier B.V. |
| سنة النشر: | 2019 |
| المجموعة: | Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP |
| مصطلحات موضوعية: | Fered-Fenton processes, UVA photolysis, BDD anode, Flow electrolysis, Degradation intermediates |
| الوصف: | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) ; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; CNPq: 152361/2016-2 ; CNPq: 311970/2017-6 ; CAPES: AUXPE 499/2013 ; Processo FAPESP: 2004/08572-4 ; Processo FAPESP: 2018/10805-0 ; The degradation of the beta-lactam antibiotic cephalexin (CEX) was carried out by the following electrochemical advanced oxidation processes (EAOPs): anodic oxidation (AO), Fered-Fenton (EF-Fered), photoassisted anodic oxidation (PAO), and photoassisted Fered-Fenton (PEF-Fered). All experiments were done in a flow reactor incorporating a boron-doped diamond anode, at a low current density; for the PAO and PEF-Fered processes, the solution was irradiated with UVA light. The initial removal of CEX was attained by all EAOPs, but it was much faster by the Fenton-based processes, which thus presented higher initial rates of TOC removal. However, the coupling of the electrolytic and UVA photolytic processes enhanced the mineralization process; as a consequence, significantly greater TOC removals were attained by the PEF-Fered and PAO processes. From the initial oxidation intermediates detected by LC-MS/MS for the PEF-Fered and AO processes, it could be concluded that addition reactions involving the electrophilic HO center dot radicals occurred preferentially in the beta-lactam ring; however, due to the higher availability of HO center dot radicals, the Fenton-based process led to a faster rupture of that ring. Thus, the antibacterial activity of the treated CEX solution against Escherichia coli was completely terminated within less than 1 h of treatment by the PEF-Fered process, compared to 8 h by the AO process. The PEF-Fered and PAO processes yielded enhanced degradation performances despite mere use of UVA light. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 1104-1112 |
| اللغة: | English |
| تدمد: | 1385-8947 |
| Relation: | Chemical Engineering Journal; http://dx.doi.org/10.1016/j.cej.2019.04.185; Chemical Engineering Journal. Lausanne: Elsevier Science Sa, v. 372, p. 1104-1112, 2019.; http://hdl.handle.net/11449/185806; WOS:000471670400103 |
| DOI: | 10.1016/j.cej.2019.04.185 |
| الاتاحة: | http://hdl.handle.net/11449/185806 https://doi.org/10.1016/j.cej.2019.04.185 |
| Rights: | openAccess |
| رقم الانضمام: | edsbas.29CD5F2B |
| قاعدة البيانات: | BASE |
| تدمد: | 13858947 |
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| DOI: | 10.1016/j.cej.2019.04.185 |