Academic Journal

Radiation therapy duration influences overall survival in patients with cervix carcinoma.

التفاصيل البيبلوغرافية
العنوان: Radiation therapy duration influences overall survival in patients with cervix carcinoma.
المؤلفون: Coucke, Philippe, Delaloye, J-F, Pampallona, S, Peltecu, G, De Grandi, P
المصدر: International Journal of Gynecology and Obstetrics, 57, 295-303 (1997)
بيانات النشر: Elsevier
سنة النشر: 1997
المجموعة: University of Liège: ORBi (Open Repository and Bibliography)
مصطلحات موضوعية: Treatment time, Overrall survival, radiation therapy, cervical carcinoma, Human health sciences, Hematology, Oncology, Sciences de la santé humaine, Hématologie, Oncologie
الوصف: peer reviewed ; of the cervix treated by radical radiation therapy. Method; Three hundred and sixty patients with FIG0 stage IB-IIIB carcinoma of the cervix were treated in Lausanne (Switzerland) with external radiation and brachytherapy as first line therapy. Median therapy duration was 45 days. Patients were classified according to the duration of the therapies, taking 60 days (the 75th percentile) as an arbitrary cut-off. Results: The 5-year survival was 61% (SE. = 3%) for the therapy duration group of less than 60 days and 53% (SE. = 7%) for the group of more than 60 days. In terms of univariate hazard ratio (HR), the relative difference between the hvo groups corresponds to a 50% increase of deaths (HR = 1.53, 95% CI = 1.03-2.28) for the longer therapy duration group (P = 0.044). In a multivariate analysis, the magnitude of estimated relative hazards for the longer therapies are confirmed though significance was reduced (HR = 1.52, 95% CI = 0.94-2.45, P = 0.084). Conclusion: These findings suggesthat short treatment duration is a factor associated with longer survival in carcinoma of the cervix. 0 1997 International Federation of Gynecology and Obstetrics
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0020-7292
1879-3479
Relation: urn:issn:0020-7292; urn:issn:1879-3479; https://orbi.uliege.be/handle/2268/17000; info:hdl:2268/17000; https://orbi.uliege.be/bitstream/2268/17000/1/radiation%20therapy%20duration%20influences%20overall%20survival%201997%20vol%2057.pdf; info:pmid:9215493
DOI: 10.1016/S0020-7292(97)02888-9
الاتاحة: https://orbi.uliege.be/handle/2268/17000
https://orbi.uliege.be/bitstream/2268/17000/1/radiation%20therapy%20duration%20influences%20overall%20survival%201997%20vol%2057.pdf
https://doi.org/10.1016/S0020-7292(97)02888-9
Rights: open access ; http://purl.org/coar/access_right/c_abf2 ; info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.28E99EFF
قاعدة البيانات: BASE
الوصف
تدمد:00207292
18793479
DOI:10.1016/S0020-7292(97)02888-9