Academic Journal
Walnut Seed Coat (Juglans regia L.), a Plant Effective in Human Health: Antioxidant Activity and in Rats Nephroprotective Effect
| العنوان: | Walnut Seed Coat (Juglans regia L.), a Plant Effective in Human Health: Antioxidant Activity and in Rats Nephroprotective Effect |
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| المؤلفون: | Hülya Akıncıoğlu, Seda Aşkın, Hakan Aşkın, Handan Uğuz, Esra Palabıyık |
| المصدر: | Research in Agricultural Sciences, Vol 55, Iss 2, Pp 89-104 (2024) |
| بيانات النشر: | Atatürk University |
| سنة النشر: | 2024 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | antioksidan aktivite, böbrek, oksidatif stress, triton wr-1339, ceviz tohumu kabuğu, antioxidant activity, kidney, oxidative stress, walnut seed coat, Agriculture |
| الوصف: | In the study, the seed coat (WSC) of Posof (Ardahan/Türkiye) walnuts was extracted to determine their phytochemical components and antioxidant capacities. The effects of bioactive components in the ethanol extract of WSC (E-WSC) on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors were investigated. Additionally, antioxidant enzyme activity parameters were measured in the kidney tissues of Triton WR-1339-induced hyperlipidemic rats. Bioactive compounds in WSC were identified by GC-MS system. The antioxidant properties of WSC were measured using Fe+3, Cu+2 and Fe+3-2,4,6-tripyridyl-s-triazine (TPTZ) reducing agent, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'- azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) scavenging activities. In this analysis, using 30 male Wistar rats (300 ± 30 g) randomly divided into five groups were treated as follows; K1: Healthy control group, K2: E-WSC (150 mg) o.d., K3: E-WSC (300 mg) o.d., K4: Hyperlipidemic group i.p., K5: Hyperlipidemic group i.p. + E-WSC (300 mg) o.d. Superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) analyzes were performed in kidney tissues. Based on these results, it was clearly determined that E-WSC has significant antioxidant activity due to its bioactive components, has an inhibitory effect on AChE and BChE enzymes, and has a protective effect against oxidative stress by improving hyperlipidemia-related kidney damage. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Turkish |
| Relation: | https://dergipark.org.tr/en/download/article-file/3654101; https://doaj.org/toc/2979-9686; https://doaj.org/article/f53b15e9b2ac468794644e332fceb0ea |
| DOI: | 10.17097/agricultureatauni.1418238 |
| الاتاحة: | https://doi.org/10.17097/agricultureatauni.1418238 https://doaj.org/article/f53b15e9b2ac468794644e332fceb0ea |
| رقم الانضمام: | edsbas.28328C78 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17097/agricultureatauni.1418238 |
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