التفاصيل البيبلوغرافية
| العنوان: |
Experimental poisoning of goats by Ipomoea carnea subsp. fistulosa in Argentina : a clinic and pathological correlation with special consideration on the central nervous system |
| المؤلفون: |
Ríos, Elvio Eduardo, Cholich, Luciana Andrea, Gimeno, Eduardo Juan, Guidi, María Guadalupe, Acosta, Ofelia Cristina |
| المصدر: |
Pesquisa Veterinária Brasileira, 2012, vol. 32, no. 1, p. 37-42. |
| بيانات النشر: |
Colégio Brasileiro de Patologia Animal |
| سنة النشر: |
2012 |
| المجموعة: |
Repositorio Institucional de la Universidad Nacional del Nordeste (RIUNNE) |
| مصطلحات موضوعية: |
Poisonous plants, Ipomoea carnea, Plant poisoning, Goats, CNS lesions, Transmission electron microscopy, Plantas toxicas, Caprinos, Intoxicacao por planta, CNS lesoes, Microscopia eletronica de transmissao |
| الوصف: |
Ipomoea carnea subsp. _istulosa, aguapei or mandiyura, is responsible for lysosomal storage in goats. The shrub contains several alkaloids, mainly swansonine which inhibits lysosomal α-mannosidase and Golgi mannosidase II. Poisoning occurs by inhibition of these hydrolases. There is neuronal vacuolation, endocrine dysfunction, cardiovascular and gastrointestinal injury, and immune disorders. Clinical signs and pathology of the experimental poisoning of goatsby Ipomoea carnea in Argentina are here described. Five goats received fresh leaves and stems of Ipomoea. At the beginning, the goats did not consume the plant, but later, it was preferred over any other forage. High dose induced rapid intoxication, whereas with low doses, the course of the toxicosis was more protracted. The goats were euthanized when they were recumbent. Cerebrum, cerebellum, medulla oblongata, pons and colliculi, were routinely processed for histology. In nine days, the following clinical signs developed: abnormal fascies, dilated nostrils and abnormal postures of the head, cephalic tremors and nystagmus, dif_iculty in standing. Subsequently, the goats had a tendency to fall, always to the left, with spastic convulsions.There was lack in coordination of voluntary movements due to Purkinje and deep nuclei neurons damage. The cochlear re_lex originated hyperre_lexia, abnormal posture, head movements and tremors. The withdrawal re_lex produced _lexor muscles hypersensitivity at the four legs, later depression and stupor. Abnormal responses to sounds were related to collicular lesions. Thalamic damage altered the withdrawal re_lex, showing incomplete reaction. The observed cervical hair bristling was attributed to a thalamic regulated nociceptive response. Depression may be associated with agonists of lysergic acid contained in Ipomoea. These clinical signs were correlated with lesions in different parts of the CNS. ; Ipomoea carnea subsp. fistulosa, aguapeí ou mandiyura, causa uma doenca de depósito lisossomal em caprinos. A planta contém ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf; p. 37-42 |
| اللغة: |
English |
| تدمد: |
0100-736X |
| Relation: |
Ríos, Elvio Eduardo, et al., 2012. Experimental poisoning of goats by Ipomoea carnea subsp.fistulosa in Argentina : a clinic and pathological correlation with special consideration on the central nervous system. Pesquisa Veterinária Brasileira. Rio de Janeiro: Colégio Brasileiro de Patologia Animal, vol. 32, no. 1, p. 37-42. E-ISSN 1678-5150.; http://repositorio.unne.edu.ar/handle/123456789/53209 |
| الاتاحة: |
http://repositorio.unne.edu.ar/handle/123456789/53209 |
| Rights: |
openAccess ; http://creativecommons.org/licenses/by-nc-nd/2.5/ar/ |
| رقم الانضمام: |
edsbas.27F1F6A1 |
| قاعدة البيانات: |
BASE |