التفاصيل البيبلوغرافية
| العنوان: |
TASOR PARP- like domain is involved in DCAF1 binding. |
| المؤلفون: |
Michaël M. Martin (11608140), Roy Matkovic (5178071), Pauline Larrous (11608143), Marina Morel (77462), Angélique Lasserre (11608146), Virginie Vauthier (11608149), Florence Margottin-Goguet (77467) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Science Policy, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, viral auxiliary proteins, terminal parp -<, integrated viral dna, blocks viral expression, hush restriction independently, vpx mutants ability, reduced binding affinity, div >< p, 1 minigenome expression, mediated hush degradation, degrade tasor correlated, still degrading samhd1, trigger tasor degradation, dcaf1 distinguishes tasor, vpx bridges samhd1, degrade tasor |
| الوصف: |
( A ) Schematic representation of HA-tagged TASOR or Flag-tagged TASOR constructs. 1–1670 : TASOR long isoform. 1–1512 : TASOR short isoform. 1–931 : N-terminal fragment of TASOR. 630–1512 : C-terminal fragment of TASOR short isoform. WT : TASOR (short isoform). ΔPARP : TASOR (short isoform) deleted of its PARP- like domain (106–319 aa). ( B ) Indicated HA-TASOR constructions were expressed in HeLa cells, then an anti-HA immunoprecipitation was performed. ( C ) Flag-Vpx WT and indicated HA-TASOR constructs were co-expressed in HeLa cells, then an anti-Flag immunoprecipitation was performed. ( D ) TASOR-Flag WT or TASOR-ΔPARP-Flag were co-expressed with HA-Vpx WT in HeLa cells, then an anti-Flag immunoprecipitation was performed. In each panel, the indicated proteins were revealed by western blot. For this figure, each shown immunoblot is representative of at least 3 independent experiments. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/TASOR_PARP-_i_like_i_domain_is_involved_in_DCAF1_binding_/16878639 |
| DOI: |
10.1371/journal.ppat.1009609.g002 |
| الاتاحة: |
https://doi.org/10.1371/journal.ppat.1009609.g002 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.27B563B |
| قاعدة البيانات: |
BASE |