التفاصيل البيبلوغرافية
| العنوان: |
Multidrug-Resistant Tuberculosis in U.S.-Bound Immigrants and Refugees |
| المؤلفون: |
Liu, Yecai, Posey, Drew L., Yang, Quanhe, Weinberg, Michelle S., Maloney, Susan A., Lambert, Lauren A., Ortega, Luis S., Marano, Nina, Cetron, Martin S., Phares, Christina R. |
| المصدر: |
Ann Am Thorac Soc |
| بيانات النشر: |
American Thoracic Society |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
Original Research, socio, scipo |
| الوصف: |
RATIONALE: Approximately two-thirds of new cases of tuberculosis (TB) in the United States are among non–U.S.-born persons. Culture-based overseas TB screening in U.S.-bound immigrants and refugees has substantially reduced the importation of TB into the United States, but it is unclear to what extent this program prevents the importation of multidrug-resistant TB (MDR-TB). OBJECTIVES: To study the epidemiology of MDR-TB in U.S.-bound immigrants and refugees and to evaluate the effect of culture-based overseas TB screening in U.S.-bound immigrants and refugees on reducing the importation of MDR-TB into the United States. METHODS: We analyzed data of immigrants and refugees who completed overseas treatment for culture-positive TB during 2015–2019. We also compared mean annual number of MDR-TB cases in non–U.S.-born persons within 1 year of arrival in the United States between 1996–2006 (when overseas screening followed a smear-based algorithm) and 2014–2019 (after full implementation of a culture-based algorithm). RESULTS: Of 3,300 culture-positive TB cases identified by culture-based overseas TB screening in immigrants and refugees during 2015–2019, 122 (3.7%; 95% confidence interval [CI], 3.1–4.1) had MDR-TB, 20 (0.6%; 95% CI, 0.3–0.9) had rifampicin-resistant TB, 382 (11.6%; 95% CI, 10.5–12.7) had isoniazid-resistant TB, and 2,776 (84.1%; 95% CI, 82.9–85.4) had rifampicin- and isoniazid-susceptible TB. None were diagnosed with extensively drug-resistant TB. All 3,300 persons with culture-positive TB completed treatment overseas; of 70 and 11 persons who were treated overseas for MDR-TB and rifampicin-resistant TB, respectively, none were diagnosed with TB disease at postarrival evaluation in the United States. Culture-based overseas TB screening in U.S.-bound immigrants and refugees prevented 24.4 MDR-TB cases per year from arriving in the United States, 18.2 cases more than smear-based overseas TB screening. The mean annual number of MDR-TB cases among non–U.S.-born persons within 1 year of arrival in the . |
| نوع الوثيقة: |
text |
| اللغة: |
English |
| Relation: |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169124/ |
| الاتاحة: |
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169124/ |
| Rights: |
undefined |
| رقم الانضمام: |
edsbas.275820B6 |
| قاعدة البيانات: |
BASE |