Academic Journal
Revised upper limb module for spinal muscular atrophy: Development of a new module
| العنوان: | Revised upper limb module for spinal muscular atrophy: Development of a new module |
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| المؤلفون: | Mazzone, Elena S., Mayhew, Anna, Montes, Jacqueline, Ramsey, Danielle, Fanelli, Lavinia, Young, Sally Dunaway, Salazar, Rachel, De Sanctis, Roberto, Pasternak, Amy, Glanzman, Allan, Coratti, Giorgia, Civitello, Matthew, Forcina, Nicola, Gee, Richard, Duong, Tina, Pane, Marika, Scoto, Mariacristina, Pera, Maria Carmela, Messina, Sonia, Tennekoon, Gihan, Day, John W., Darras, Basil T., De Vivo, Darryl C., Finkel, Richard, Muntoni, Francesco, Mercuri, Eugenio |
| المصدر: | Muscle & Nerve ; volume 55, issue 6, page 869-874 ; ISSN 0148-639X 1097-4598 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2017 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Introduction There is a growing need for a robust clinical measure to assess upper limb motor function in spinal muscular atrophy (SMA), as the available scales lack sensitivity at the extremes of the clinical spectrum. We report the development of the Revised Upper Limb Module (RULM), an assessment specifically designed for upper limb function in SMA patients. Methods An international panel with specific neuromuscular expertise performed a thorough review of scales currently available to assess upper limb function in SMA. This review facilitated a revision of the existing upper limb function scales to make a more robust clinical scale. Results Multiple revisions of the scale included statistical analysis and captured clinically relevant changes to fulfill requirements by regulators and advocacy groups. Conclusions The resulting RULM scale shows good reliability and validity, making it a suitable tool to assess upper extremity function in the SMA population for multi‐center clinical research. Muscle Nerve 55 : 869–874, 2017 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/mus.25430 |
| الاتاحة: | https://doi.org/10.1002/mus.25430 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fmus.25430 https://onlinelibrary.wiley.com/doi/pdf/10.1002/mus.25430 https://onlinelibrary.wiley.com/doi/full-xml/10.1002/mus.25430 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.273901D7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/mus.25430 |
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