Academic Journal
Performance based on NEMA NU-4 2008 Standard of CDTN/CNEN’s Small Animal PET Scanner
| العنوان: | Performance based on NEMA NU-4 2008 Standard of CDTN/CNEN’s Small Animal PET Scanner |
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| المؤلفون: | Rodrigo Modesto Gadelha Gontijo, Andréa Vidal Ferreira, Juliana Batista da Silva, Marcelo Mamede |
| المصدر: | Brazilian Journal of Radiation Sciences, Vol 10, Iss 3 (2022) |
| بيانات النشر: | Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | quality control, NEMA NU 4-2008, Preclinical PET, Science |
| الوصف: | This study aimed to evaluate the general performance of the preclinical PET scanner (LabPET Solo 4, GE) at CDTN/CNEN using the NEMA NU 4-2008 protocol. The performance parameters include: (i) spatial resolution; (ii) scatter fraction and counts rate performance; (iii) sensitivity and (iv) image quality. For the evaluation specific simulators and a sealed radioactive source of Sodium-22 were used. The results revealed that the NEMA-based radial spatial resolution ranged from 1.79 mm at the center of the FOV to 2.49 mm at a radial offset of 25mm. Tangential resolution ranged from 1.95mm at the center of the FOV to 3.50mm at a radial offset of 25mm. Axial resolution ranged from 1.78mm at the center of the FOV to 5.42mm at a radial offset of 25mm. Iterative image reconstruction improved the radial spatial resolution to 0.93mm at the center of the FOV. For the mouse-sized phantom, the peak noise equivalent count rate (NECR) was 37.8kcps at 85MBq whereas the peak true count rate was 169.9kcps at 125MBq with a count loss of 7.8% for the maximum rate reached at 103.3MBq. The peak of sensitivity (S) and absolute sensitivity (SA) at the center of axial field-of-view (FOV) is 5.7cps.Bq-1 and 0.63%, respectively. The overall imaging capabilities of the scanner were assessed using the NEMA image-quality phantom. The image roughness was 9.5%. Spillover rates (SORs) in air and in water were 0.26 and 0.17 respectively. The recovery coefficients (RCs) were 0.12 for the 1-mm-diameter rod and 0.91 for the 5-mm-diameter rod. The results demonstrate that CDTN/CNENsmall animal PET scanner has adequate reliability and acquired images are compatible with international quality standards for the molecular imaging research. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Portuguese |
| تدمد: | 2319-0612 |
| Relation: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/2006; https://doaj.org/toc/2319-0612; https://doaj.org/article/419ec22d3de7436aa2a6be3c778ee9a4 |
| DOI: | 10.15392/bjrs.v10i3.2006 |
| الاتاحة: | https://doi.org/10.15392/bjrs.v10i3.2006 https://doaj.org/article/419ec22d3de7436aa2a6be3c778ee9a4 |
| رقم الانضمام: | edsbas.273031BE |
| قاعدة البيانات: | BASE |
| تدمد: | 23190612 |
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| DOI: | 10.15392/bjrs.v10i3.2006 |