Academic Journal
Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes
| العنوان: | Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes |
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| المؤلفون: | Zhongying Wang, Tatyana Gurlo, Aleksey V. Matveyenko, David Elashoff, Peiyu Wang, Madeline Rosenberger, Jason A. Junge, Raymond C. Stevens, Kate L. White, Scott E. Fraser, Peter C. Butler |
| المصدر: | Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021) |
| بيانات النشر: | Nature Portfolio |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Biology (General), QH301-705.5 |
| الوصف: | Using phasor-FLIM (Fluorescence Lifetime Imaging Microscopy), Wang et al. reveal differential usages of oxidative phosphorylation and glycolysis in living islet cells following glucose stimulation. This study suggests the applicability of FLIM as a drug discovery tool as it reports perturbations in glucose metabolism in living islet cells. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2399-3642 |
| Relation: | https://doi.org/10.1038/s42003-021-02113-1; https://doaj.org/toc/2399-3642; https://doaj.org/article/16706c9faa644994ba8974540e742fe0 |
| DOI: | 10.1038/s42003-021-02113-1 |
| الاتاحة: | https://doi.org/10.1038/s42003-021-02113-1 https://doaj.org/article/16706c9faa644994ba8974540e742fe0 |
| رقم الانضمام: | edsbas.270833F1 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23993642 |
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| DOI: | 10.1038/s42003-021-02113-1 |