Academic Journal

Prevalence of river epilepsy in the Orientale province in the Democratic Republic of the Congo

التفاصيل البيبلوغرافية
العنوان: Prevalence of river epilepsy in the Orientale province in the Democratic Republic of the Congo
المؤلفون: Colebunders, Robert, Tepage, Floribert, Rood, Ente, Mandro, Michel, Abatih, Emmanuel Nji, Musinya, Gisele, Mambandu, Germain, Kabeya, Jose, Komba, Michel, Levick, Bethany, Mokili, John L., Laudisoit, Anne
المصدر: 1935-2727 ; PLoS neglected tropical diseases
سنة النشر: 2016
المجموعة: IRUA - Institutional Repository van de Universiteit Antwerpen
مصطلحات موضوعية: Human medicine
الوصف: Background An increased prevalence of epilepsy has been reported in many onchocerciasis endemic areas. Objective To determine the prevalence and distribution of epilepsy in an onchocerciasis endemic region in the Democratic Republic of the Congo (DRC). Design/Methods An epilepsy prevalence study was carried out in 2014, in two localities of the Bas-Uele district, an onchocerciasis endemic region in the Orientale Province of the DRC. Risk factors for epilepsy were identified using a random effects logistic regression model and the distribution of epilepsy cases was investigated using the Moran's I statistic of spatial auto-correlation. Results Among the 12,776 individuals of Dingila, 373 (2.9%) individuals with epilepsy were identified. In a house-to-house survey in Titule, 68 (2.3%) of the 2,908 people who participated in the survey were found to present episodes of epilepsy. Epilepsy showed a marked spatial pattern with clustering of cases occurring within and between adjacent households. Individual risk of epilepsy was found to be associated with living close to the nearest fast flowing river where blackflies (Diptera: Simuliidae)- the vector of Onchocerca volvulus-oviposit and breed. Conclusions The prevalence of epilepsy in villages in the Bas-Uele district in the DRC was higher than in non-onchocerciasis endemic regions in Africa. Living close to a blackflies infested river was found to be a risk factor for epilepsy.
نوع الوثيقة: article in journal/newspaper
وصف الملف: pdf
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/isi/000377769300002
الاتاحة: https://hdl.handle.net/10067/1346090151162165141
https://repository.uantwerpen.be/docman/irua/424242/134609.pdf
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.26E01B2C
قاعدة البيانات: BASE