Single base substitution mutation profiles of individual granddaughter clones by whole genome sequencing.

التفاصيل البيبلوغرافية
العنوان: Single base substitution mutation profiles of individual granddaughter clones by whole genome sequencing.
المؤلفون: Michael A. Carpenter, Nuri A. Temiz, Mahmoud A. Ibrahim, Matthew C. Jarvis, Margaret R. Brown, Prokopios P. Argyris, William L. Brown, Gabriel J. Starrett, Douglas Yee, Reuben S. Harris
سنة النشر: 2023
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, whole genome sequences, triggers increased frequencies, stranded loop regions, standing etiologic debate, local sequence preferences, independent clones enabled, human cell line, catalytic mutant controls, 70 %, suggesting, thymidine kinase <, quantify genome mutation, overall mutation landscape, cellular apobec3 enzymes, div >< p, apobec3 signature mutations, although multiple enzymes, tk <, g mutations
الوصف: Trinucleotide profiles of all SBS mutations in WGSs from the indicated granddaughter clones (conditions, clone names, and total SBS numbers are indicated to the right in each profile). Aggregate profiles for A3A, A3B, and corresponding catalytic mutant controls are shown in Fig 3 . (TIF)
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Single_base_substitution_mutation_profiles_of_individual_granddaughter_clones_by_whole_genome_sequencing_/24696772
DOI: 10.1371/journal.pgen.1011043.s012
الاتاحة: https://doi.org/10.1371/journal.pgen.1011043.s012
https://figshare.com/articles/figure/Single_base_substitution_mutation_profiles_of_individual_granddaughter_clones_by_whole_genome_sequencing_/24696772
Rights: CC BY 4.0
رقم الانضمام: edsbas.26A8BA2A
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pgen.1011043.s012