Academic Journal
MtDNA phylogeny and evolution of laboratory mouse strains
| العنوان: | MtDNA phylogeny and evolution of laboratory mouse strains |
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| المؤلفون: | Goios, A, Pereira, L, Bogue, M, Macaulay, V, Amorim, A |
| المساهمون: | Instituto de Investigação e Inovação em Saúde |
| بيانات النشر: | Cold Spring Harbor Laboratory Press |
| سنة النشر: | 2007 |
| المجموعة: | Repositório Aberto da Universidade do Porto |
| مصطلحات موضوعية: | Animals, Base Sequence, DNA Mitochondrial/genetics, Female, Genetic Variation, Likelihood Functions, Mice, Mice Inbred Strains/genetics, Models, Genetic, Molecular Sequence Data, Phylogeny, Sequence Analysis DNA |
| الوصف: | Inbred mouse strains have been maintained for more than 100 years, and they are thought to be a mixture of four different mouse subspecies. Although genealogies have been established, female inbred mouse phylogenies remain unexplored. By a phylogenetic analysis of newly generated complete mitochondrial DNA sequence data in 16 strains, we show here that all common inbred strains descend from the same Mus musculus domesticus female wild ancestor, and suggest that they present a different mitochondrial evolutionary process than their wild relatives with a faster accumulation of replacement substitutions. Our data complement forthcoming results on resequencing of a group of priority strains, and they follow recent efforts of the Mouse Phenome Project to collect and make publicly available information on various strains. ; This work was partially supported by Fundação para a Ciência e a Tecnologia through a research grant to A.G. (SFRH/BD/16518/2004) and by “Programa Operacional Ciência, e Inovação 2010” (POCI 2010), VI Programa-Quadro (2002–2006). |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf; application/msword |
| اللغة: | English |
| تدمد: | 1088-9051 |
| Relation: | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F16518%2F2004/PT; Genome Research, vol. 17(3), p. 293-8; http://genome.cshlp.org/content/17/3/293.long; http://hdl.handle.net/10216/109266 |
| DOI: | 10.1101/gr.5941007 |
| الاتاحة: | http://hdl.handle.net/10216/109266 https://doi.org/10.1101/gr.5941007 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.2668C9D8 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 10889051 |
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| DOI: | 10.1101/gr.5941007 |