التفاصيل البيبلوغرافية
| العنوان: |
Loci with significant interaction between fish oil supplementation and blood lipid levels. |
| المؤلفون: |
Michael Francis (287202), Changwei Li (525465), Yitang Sun (10428718), Jingqi Zhou (4489816), Xiang Li (114679), J. Thomas Brenna (63512), Kaixiong Ye (3456233) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Genetics, Ecology, Mental Health, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, novel interaction loci, gene-diet interaction loci Fish oil., ARIC, TAG, genes SLC 12A, GJB 2 expression, blood lipids, gene-diet interaction effects, HDL-C, Significant interaction effects, UK, ABCA, 1 df P, fish oil supplementation, Genome-wide association study, interaction effects, MLXIPL, GJA 3 gene cluster, novel gene-diet interaction effects, LDL-C |
| الوصف: |
Listed variants represent the lead association within a 1 Mb region for 1df tests of variant × fish oil interaction after meta-analysis. The name of the nearest gene is listed with each lead variant. Bold P -values indicate meeting the genome-wide significance threshold of P < 5 × 10 −8 . Main effect P -values are calculated using Stage 1 (UK Biobank) participants only, and without interaction (Eq ( 2 ); stratified for exposure groups as in Eq (3) ). Effect, beta coefficient of the minor allele dose term (β G in Eq (1) ); MAF, minor allele frequency; SE, standard error; Int effect, beta coefficient of the interaction term (β G×E G×E in Eq (1) ). Lipid traits were measured in mmol/L. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/dataset/Loci_with_significant_interaction_between_fish_oil_supplementation_and_blood_lipid_levels_/14302505 |
| DOI: |
10.1371/journal.pgen.1009431.t001 |
| الاتاحة: |
https://doi.org/10.1371/journal.pgen.1009431.t001 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.2632A14 |
| قاعدة البيانات: |
BASE |