Academic Journal
Nivolumab-induced exocrine pancreatic insufficiency
| العنوان: | Nivolumab-induced exocrine pancreatic insufficiency |
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| المؤلفون: | Jones, Anna, Rodgers, Kay, Jeffrey, Debbie, Ali, Waqas I, Andreyev, HJN |
| المصدر: | Frontline Gastroenterology ; volume 14, issue 2, page 167-170 ; ISSN 2041-4137 2041-4145 |
| بيانات النشر: | BMJ |
| سنة النشر: | 2021 |
| الوصف: | Immune checkpoint inhibition is the standard-of-care for many advanced cancers. Side effects of therapy may prevent optimal treatment of the cancer. Management of side effects is dominated by recommendations derived from oncological, not gastroenterological practice. We report a patient who developed pancreatic insufficiency during checkpoint inhibitor therapy with a programmed cell death receptor 1 inhibitor, nivolumab, which if not diagnosed would have prevented ongoing treatment. This is a problem which affects approximately 1 in 100 patients treated with this agent but is rarely recognised. Gastroenterologists need to be aware of the spectrum of gastrointestinal disorders which occur after immunotherapy to treat cancer. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1136/flgastro-2021-102013 |
| الاتاحة: | http://dx.doi.org/10.1136/flgastro-2021-102013 https://syndication.highwire.org/content/doi/10.1136/flgastro-2021-102013 |
| رقم الانضمام: | edsbas.26143E7C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/flgastro-2021-102013 |
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