Academic Journal
Comparison between the stripping technique and the combined excisional/ablative technique for the treatment of bilateral ovarian endometriomas : a multicentre RCT
| العنوان: | Comparison between the stripping technique and the combined excisional/ablative technique for the treatment of bilateral ovarian endometriomas : a multicentre RCT |
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| المؤلفون: | L. Muzii, C. Achilli, V. Bergamini, M. Candiani, E. Garavaglia, L. Lazzeri, F. Lecce, A. Maiorana, F. Maneschi, R. Marana, A. Perandini, M. G. Porpora, R. Seracchioli, E. Spagnolo, P. Benedetti Panici, M. Vignali |
| المساهمون: | L. Muzii, C. Achilli, V. Bergamini, M. Candiani, E. Garavaglia, L. Lazzeri, F. Lecce, A. Maiorana, F. Maneschi, R. Marana, A. Perandini, M.G. Porpora, R. Seracchioli, E. Spagnolo, M. Vignali, P. Benedetti Panici |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2016 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | antral follicle count, endometrioma, endometriosi, ovarian reserve, ovarian surgery, Settore MED/40 - Ginecologia e Ostetricia |
| الوصف: | STUDY QUESTION: Is the combined excisional/ablative technique for the treatment of ovarian endometriomas better than the traditional stripping technique in terms of recurrence rate? SUMMARY ANSWER: There is no evidence that the combined excisional/ablative technique is better than the traditional stripping technique, as similar recurrence rates were observed for the two techniques. WHAT IS KNOWN ALREADY: The stripping technique is associated with better results compared with ablative, non-excisional techniques for the treatment of ovarian endometriomas. Excisional techniques, such as stripping, have, however, been associated with reduced ovarian reserve as evaluated with anti-Mullerian hormone, and surgical techniques that better preserve the ovarian reserve are needed. STUDY DESIGN, SIZE, DURATION: A prospective, multicentre, randomized blinded clinical trial was carried out on 51 patients with bilateral endometriomas larger than 3 cm. For each patient, serving as her own control, one ovary was randomized to the stripping technique and the contralateral to the combined excisional/ablative technique. Patients were enrolled between January 2013 and April 2014. PARTICIPANTS/MATERIALS, SETTING, METHODS: Patients of reproductive age with pelvic pain and/or infertility affected by bilateral endometriomas larger than 3 cm were included (n = 51). The patients underwent laparoscopic removal of endometriomas with two different surgical techniques performed at either side after random assignment: complete removal by stripping on one side versus the combined technique, consisting of partial excisional cystectomy followed by completion with ablative surgery using bipolar coagulation, on the other side. Post-operative follow-up was performed at 1, 3 and 6 months after surgery for the evaluation of endometrioma recurrence (primary outcome) and of antral follicle count (AFC) and ovarian volumes (OVs) to assess ovarian reserve (secondary outcome). MAIN RESULTS AND THE ROLE OF CHANCE: Recurrence rates were 5.9% for the stripping ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/26682578; info:eu-repo/semantics/altIdentifier/wos/WOS:000371149400013; volume:31; issue:2; firstpage:339; lastpage:344; numberofpages:6; journal:HUMAN REPRODUCTION; http://hdl.handle.net/2434/359382; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84983164437 |
| DOI: | 10.1093/humrep/dev313 |
| الاتاحة: | http://hdl.handle.net/2434/359382 https://doi.org/10.1093/humrep/dev313 |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.25F4255 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/humrep/dev313 |
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