Academic Journal

Candida keratitis and endopthalmitis after corneal transplantation; two case reports, a novel regimen and literature overview of therapeutic options

التفاصيل البيبلوغرافية
العنوان: Candida keratitis and endopthalmitis after corneal transplantation; two case reports, a novel regimen and literature overview of therapeutic options
المؤلفون: van der Wekken-Pas, L. C., de Haas, P. J., Wisse, R., Rados, M., van der Elst, K. C.M.
المساهمون: MS Oogheelkunde, Research UMC Utrecht, Infection & Immunity, Brain, Apotheek Klinische Farmacie
سنة النشر: 2023
مصطلحات موضوعية: antifungals, corneal transplantation, endophtalmitis, fungal infection, Keratitis, pharmacotherapy, Ophthalmology, Journal Article
الوصف: Purpose: To evaluate treatment options for candida keratitis and endopthalmitis after corneal transplantation. Methods: Case reports and literature review. Results: Two patients with keratitis due to Candida glabrata/parapsilosis after corneal transplantation were successfully treated with a combination of topical voriconazole, intracameral voriconazole and amphotericin B, and systemic treatment with flucytosine. Conclusions: Natamycine and voriconazole topically are preferred therapeutic options for the treatment of fungal keratitis. Systemic flucytosine is a useful alternative additive, particularly for countries where natamycine is not registered as a pharmaceutical agent.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
تدمد: 1120-6721
Relation: https://dspace.library.uu.nl/handle/1874/444744
الاتاحة: https://dspace.library.uu.nl/handle/1874/444744
Rights: info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.25E54A6D
قاعدة البيانات: BASE