Academic Journal

Primary screening for cervical cancer through self sampling

التفاصيل البيبلوغرافية
العنوان: Primary screening for cervical cancer through self sampling
المؤلفون: Holanda, F., Castelo, A., Veras, T. M. C. W., Almeida, F. M. L. de, Lins, M. Z., Dores, G. B.
المساهمون: State Ceara Secretary Hlth, Universidade Federal de São Paulo (UNIFESP), Univ Fed Ceara
بيانات النشر: Elsevier B.V.
سنة النشر: 2006
المجموعة: Universidade Federal de São Paulo (UNIFESP): Repositório Institucional
مصطلحات موضوعية: HPV screening, cervical cancer, prevention, rural areas
الوصف: Objective: To evaluate the use of community health agents (CHAs) to instruct women living in poor rural areas in obtaining self-collected cervical samples and compare the high-risk HPV (hrHPV) hybrid capture (HC) results obtained to those for gynecologist-collected samples. Methods: After a one-day training, CHAs visited sexually active women, instructing each in the use of collection brush and the Universal Collection Medium tube. One week thereafter, a gynecologist collected cervical samples from, and performed colposcopies on, the same women. A single reference Lab performed all HCs. Results: 878 women (Age: 15-69 years) participated. Among self-collected samples, hrHPV prevalence was 33.9% (95% CI: 30.8%-37%), compared with 28.6% (95% CI: 27%-30%) among gynecologist-collected samples. However, 9.3% of the patients were HPV HC II-positive in the seff-collected sample and HPV HC II-negative in the gynecologist-collected samples (95% CI: 7.38%-11.22%), whereas 4% tested positive in gynecologist-collected samples and negative in self-collected samples (95% CI: 2.7%-5.3%) (P < 0.01; kappa=0.7). of 9 cases of histologically-confirmed, high-grade squamous intraepithelial lesion, self-collected and provider-collected samples missed one each. Conclusion: Self-collected vaginal. sampling could be made an additional CHA function under existing program conditions, improving access to cervical cancer screening in poor rural settings. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. ; State Ceara Secretary Hlth, Fortaleza, Ceara, Brazil ; UNIFESP, Sch Med, São Paulo, Brazil ; Univ Fed Ceara, Fortaleza, Ceara, Brazil ; UNIFESP, Sch Med, São Paulo, Brazil ; Web of Science
نوع الوثيقة: article in journal/newspaper
وصف الملف: 179-184
اللغة: English
تدمد: 0020-7292
Relation: International Journal of Gynecology & Obstetrics; http://dx.doi.org/10.1016/j.ijgo.2006.07.012; International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 95, n. 2, p. 179-184, 2006.; http://repositorio.unifesp.br/handle/11600/29234; WOS:000242449700024
DOI: 10.1016/j.ijgo.2006.07.012
الاتاحة: http://repositorio.unifesp.br/handle/11600/29234
https://doi.org/10.1016/j.ijgo.2006.07.012
Rights: Acesso restrito ; http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
رقم الانضمام: edsbas.25BC93E3
قاعدة البيانات: BASE
الوصف
تدمد:00207292
DOI:10.1016/j.ijgo.2006.07.012