Academic Journal
Primary screening for cervical cancer through self sampling
العنوان: | Primary screening for cervical cancer through self sampling |
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المؤلفون: | Holanda, F., Castelo, A., Veras, T. M. C. W., Almeida, F. M. L. de, Lins, M. Z., Dores, G. B. |
المساهمون: | State Ceara Secretary Hlth, Universidade Federal de São Paulo (UNIFESP), Univ Fed Ceara |
بيانات النشر: | Elsevier B.V. |
سنة النشر: | 2006 |
المجموعة: | Universidade Federal de São Paulo (UNIFESP): Repositório Institucional |
مصطلحات موضوعية: | HPV screening, cervical cancer, prevention, rural areas |
الوصف: | Objective: To evaluate the use of community health agents (CHAs) to instruct women living in poor rural areas in obtaining self-collected cervical samples and compare the high-risk HPV (hrHPV) hybrid capture (HC) results obtained to those for gynecologist-collected samples. Methods: After a one-day training, CHAs visited sexually active women, instructing each in the use of collection brush and the Universal Collection Medium tube. One week thereafter, a gynecologist collected cervical samples from, and performed colposcopies on, the same women. A single reference Lab performed all HCs. Results: 878 women (Age: 15-69 years) participated. Among self-collected samples, hrHPV prevalence was 33.9% (95% CI: 30.8%-37%), compared with 28.6% (95% CI: 27%-30%) among gynecologist-collected samples. However, 9.3% of the patients were HPV HC II-positive in the seff-collected sample and HPV HC II-negative in the gynecologist-collected samples (95% CI: 7.38%-11.22%), whereas 4% tested positive in gynecologist-collected samples and negative in self-collected samples (95% CI: 2.7%-5.3%) (P < 0.01; kappa=0.7). of 9 cases of histologically-confirmed, high-grade squamous intraepithelial lesion, self-collected and provider-collected samples missed one each. Conclusion: Self-collected vaginal. sampling could be made an additional CHA function under existing program conditions, improving access to cervical cancer screening in poor rural settings. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. ; State Ceara Secretary Hlth, Fortaleza, Ceara, Brazil ; UNIFESP, Sch Med, São Paulo, Brazil ; Univ Fed Ceara, Fortaleza, Ceara, Brazil ; UNIFESP, Sch Med, São Paulo, Brazil ; Web of Science |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | 179-184 |
اللغة: | English |
تدمد: | 0020-7292 |
Relation: | International Journal of Gynecology & Obstetrics; http://dx.doi.org/10.1016/j.ijgo.2006.07.012; International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 95, n. 2, p. 179-184, 2006.; http://repositorio.unifesp.br/handle/11600/29234; WOS:000242449700024 |
DOI: | 10.1016/j.ijgo.2006.07.012 |
الاتاحة: | http://repositorio.unifesp.br/handle/11600/29234 https://doi.org/10.1016/j.ijgo.2006.07.012 |
Rights: | Acesso restrito ; http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
رقم الانضمام: | edsbas.25BC93E3 |
قاعدة البيانات: | BASE |
تدمد: | 00207292 |
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DOI: | 10.1016/j.ijgo.2006.07.012 |