Academic Journal
Liver chemistry in new-onset Henoch-Schönlein syndrome
| العنوان: | Liver chemistry in new-onset Henoch-Schönlein syndrome |
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| المؤلفون: | G. Rosti, G.P. Milani, E.A. Laicini, FOSSALI, EMILIO FILIPPO, M. G. Bianchetti |
| المساهمون: | G. Rosti, G.P. Milani, E.A. Laicini, F. EMILIO FILIPPO, M.G. Bianchetti |
| بيانات النشر: | BioMed Central |
| سنة النشر: | 2017 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | vasculiti, allergic purpura, hepatiti, elevated liver enzyme, diagnostic test, Settore MED/38 - Pediatria Generale e Specialistica |
| الوصف: | Background: Henoch-Schonlein syndrome is a systemic small-vessel leukocytoclastic vasculitis that usually present with cutaneous, gastrointestinal, articular and renal manifestations. Little is known on liver involvement in this syndrome. This study investigated liver chemistry and creatine kinase in Henoch-Schonlein children. Case presentation: Alanine aminotransferase, aspartate aminotransferase, gamma-glutamyltransferase, lactate dehydrogenase, total bilirubin, prothrombin time and creatine kinase were assessed in 75 consecutive pediatric patients (41 boys and 34 girls aged from 2.9 to 17 years) with new-onset Henoch-Schonlein syndrome. Mildly altered values were found in 7 (9%) patients (5 boys and 2 girls aged from 3.3 to 17 years). In the mentioned cases, all tests returned to normal at a 2-4-week follow-up. Conclusions: This preliminary study points out that altered and self-remitting liver parameters occur in approximately 10% of children with Henoch-Schonlein syndrome. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000411685100001; volume:43; issue:1; journal:THE ITALIAN JOURNAL OF PEDIATRICS; http://hdl.handle.net/2434/524456; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85029693739 |
| DOI: | 10.1186/s13052-017-0405-5 |
| الاتاحة: | http://hdl.handle.net/2434/524456 https://doi.org/10.1186/s13052-017-0405-5 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.23C00954 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13052-017-0405-5 |
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