Academic Journal
Peripartal feeding strategy with different n-6:n-3 ratios in sows: effect on gene expression in backfat white adipose tissue postpartum
| العنوان: | Peripartal feeding strategy with different n-6:n-3 ratios in sows: effect on gene expression in backfat white adipose tissue postpartum |
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| المؤلفون: | Papadopoulos, Georgios A, Erkens, Tim, Maes, Dominiek G. D, Peelman, Luc J, van Kempen, Theo A. T. G, Buyse, Johan, Janssens, Geert P. J |
| بيانات النشر: | CABI Pub. EDINBURGH BLDG, SHAFTESBURY RD, CB2 8RU CAMBRIDGE, ENGLAND |
| سنة النشر: | 2009 |
| المجموعة: | KU Leuven: Lirias |
| مصطلحات موضوعية: | lactating sow, n-6:n-3 ratio, ppar gamma, ppargc1a, white adipose tissue, activated receptor-gamma, ppar-gamma, fatty-acids, insulin-resistance, arachidonic-acid, messenger-rna, 3t3-l1 adipocytes, glut4 gene, tnf-alpha, leptin |
| الوصف: | The aim of this study was to describe the effects of two diets differing in n-6:n-3 ratio and prepartal feeding regime on gene expression of PPAR gamma 1a/1b, PPAR gamma 1c/1d, PPAR gamma 2, PPAR gamma coactivator 1A (PPARGC1A), GLUT4, TNF alpha, adiponectin, leptin, leptin receptor (LEPR), fatty acid binding protein 4 (FABP4), lipoprotein lipase (LPL) in sows' white adipose tissue on the first day of lactation. The relationship between mRNA expression of these genes and circulating insulin, leptin and thyroid hormones was also considered. Diets contained a low (supplemented with fish oil, f group) or a high (supplemented with sunflower oil; s group) n-6:n-3 ratio and were provided from 8 (f8, s8) or 3d (f3, s3) before parturition (onset day 8 or 3). A low n-6:n-3 ratio reduced the 1 d postpartum expression of PPAR gamma 2 and PPARGC1A but only when applied from 3 d before parturition. Circulating leptin was negatively correlated with mRNA expression of adiponectin, LEPR and LPL, whereas thyroxine was positively correlated with levels of PPARGC1A. In conclusion, the effect of dietary treatments, e.g. altering the n-6:n-3 ratio, around parturition on the expression of crucial genes in nutrient metabolism can be modulated by the duration of application before parturition. ; status: published |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0007-1145 1475-2662 |
| Relation: | British Journal of Nutrition vol:101 issue:2 pages:197-205; https://lirias.kuleuven.be/handle/123456789/335249; https://lirias.kuleuven.be/bitstream/123456789/335249/3//PapadoupoulosBJN2009fatnesspdf.pdf |
| DOI: | 10.1017/S0007114508994782 |
| الاتاحة: | https://lirias.kuleuven.be/handle/123456789/335249 https://doi.org/10.1017/S0007114508994782 https://lirias.kuleuven.be/bitstream/123456789/335249/3//PapadoupoulosBJN2009fatnesspdf.pdf |
| رقم الانضمام: | edsbas.23B19494 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00071145 14752662 |
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| DOI: | 10.1017/S0007114508994782 |