Academic Journal

Development and Validation of a Nomogram Based on Inflammatory Markers for Risk Prediction in Meige Syndrome Patients

التفاصيل البيبلوغرافية
العنوان: Development and Validation of a Nomogram Based on Inflammatory Markers for Risk Prediction in Meige Syndrome Patients
المؤلفون: Fu R, Lian W, Zhang B, Liu G, Feng X, Zhu Y, Zhou J, Zhang X, Wang S, Huo H, Wang D, Liu C, Gao S, Ma Y, Peng M
المصدر: Journal of Inflammation Research, Vol Volume 17, Pp 7721-7731 (2024)
بيانات النشر: Dove Medical Press
سنة النشر: 2024
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: meige syndrome, inflammatory marker, nomogram, lmr, sii, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
الوصف: Runing Fu,1,* Wenping Lian,1,* Bohao Zhang,2,* Gang Liu,3 Xinyu Feng,1 Yingjie Zhu,1 Jiuan Zhou,1 Xinyu Zhang,4 Shukai Wang,1 Huijuan Huo,1 Daxin Wang,1 Cui Liu,1 Saisai Gao,1 Yajie Ma,4 Mengle Peng1,* 1Department of Clinical Laboratory, The Third People’s Hospital of Henan Province, Zhengzhou, Henan, 450006, People’s Republic of China; 2Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450000, People’s Republic of China; 3The Center of Meige Syndrome, The Third People’s Hospital of Henan Province, Zhengzhou, Henan, 450006, People’s Republic of China; 4Department of Medical Affair, the Third People’s Hospital of Henan Province, Zhengzhou, Henan, 450006, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mengle Peng; Yajie Ma, Email pengmengle1990@126.com; szsyywk@sina.comPurpose: Inflammatory markers are known to be associated with many diseases, but their role in Meige syndrome (MS) remains unclear. This study aimed to develop and validate a nomogram for the risk prediction of MS based on inflammatory markers.Patient Data and Methods: Data from 448 consecutive patients with MS at the Third People’s Hospital of Henan Province between January 2022 and December 2023 were retrospectively reviewed. The MS cohort was randomly divided into separate training and validation sets. A nomogram was constructed using a multivariate logistic regression model based on data from the training set. The model’s performance was validated through cross-validation, receiver operating characteristic (ROC) curve analysis, calibration curve analysis and decision curve analysis (DCA).Results: A total of five predictors, including red blood cell distribution width (RDW), hemoglobin (HGB), high-density lipoprotein cholesterol (HDL-C), the lymphocyte-to-monocyte ratio (LMR), and the systemic immune‐inflammation index (SII), were identified using multivariate logistic regression from a total of 11 variables. The cross-validation results indicated the ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: https://www.dovepress.com/development-and-validation-of-a-nomogram-based-on-inflammatory-markers-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031; https://doaj.org/article/7787d1934f04455b834f3705e4c5be71
الاتاحة: https://doaj.org/article/7787d1934f04455b834f3705e4c5be71
رقم الانضمام: edsbas.2343C413
قاعدة البيانات: BASE