Academic Journal

Antimicrobial efficacy assessment and rheological investigation of two different hand sanitizers compared with the standard reference WHO formulation 1

التفاصيل البيبلوغرافية
العنوان: Antimicrobial efficacy assessment and rheological investigation of two different hand sanitizers compared with the standard reference WHO formulation 1
المؤلفون: Sommatis S., Capillo M. C., Maccario C., Rauso R., D'Este E., Herrera M., Castiglioni M., Mocchi R., Zerbinati N.
المساهمون: Sommatis, S., Capillo, M. C., Maccario, C., Rauso, R., D'Este, E., Herrera, M., Castiglioni, M., Mocchi, R., Zerbinati, N.
سنة النشر: 2023
المجموعة: IRInSubria - Institutional Repository Insubria (Università degli Studi dell’Insubria)
مصطلحات موضوعية: ABHS, agar diffusion test, alcohol-based hand sanitizer, antimicrobial activity, in vitro, in vivo, MBC, MIC, organoleptic feature, rheology
الوصف: (1) Background: recently, the use of alcohol-based hand sanitizers (ABHSs) has become very frequent, and an evaluation of the stability and effectiveness of their formulations is a critical topic which should be carefully considered. (2) Methods: starting from the characterization of the hand sanitizers object of the study, our interest was focused on their rheological behavior in order to confirm their intrinsic features, but also the stability of each formulation in different conditions of shear and temperature; the second aspect concerns the antimicrobial assessment through a panel of in vitro and in vivo experimental trials. (3) Results: rheological investigation confirmed good stability for the two hand sanitizers in gel formula with respect to the reference in liquid formula; the antimicrobial activity evaluation showed good efficacy of each formulation both in vitro and in vivo. (4) Conclusions: altogether, our overview presents a valid quality control assessment to ensure the stability and efficacy of an alcohol-based hand sanitizer.
نوع الوثيقة: article in journal/newspaper
وصف الملف: ELETTRONICO
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/36826278; info:eu-repo/semantics/altIdentifier/wos/WOS:000945074400001; volume:9; issue:2; firstpage:1; lastpage:15; numberofpages:15; journal:GELS; https://hdl.handle.net/11383/2151452; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85148869510
DOI: 10.3390/gels9020108
الاتاحة: https://hdl.handle.net/11383/2151452
https://doi.org/10.3390/gels9020108
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.22DB80CD
قاعدة البيانات: BASE