التفاصيل البيبلوغرافية
| العنوان: |
Additional file 3 of Myxopyronin B inhibits growth of a Fidaxomicin-resistant Clostridioides difficile isolate and interferes with toxin synthesis |
| المؤلفون: |
Madita Brauer (10951719), Jennifer Herrmann (152429), Daniela Zühlke (256444), Rolf Müller (11963), Katharina Riedel (444866), Susanne Sievers (11916127) |
| سنة النشر: |
2022 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biophysics, Biochemistry, Medicine, Microbiology, Molecular Biology, Pharmacology, Infectious Diseases, Plant Biology, Virology, Chemical Sciences not elsewhere classified, RNA polymerase inhibitors, Rifaximin, Fidaxomicin, Myxopyronin B, Clostridioides difficile, Antibiotic therapy, Antibiotic resistance, Mass spectrometry, Toxins |
| الوصف: |
Additional file 3. Western blot images for quantification of toxin levels in C. difficile cells after stress with sublethal concentrations of Rifaximin (1.75 ng/ml; Rif), Fidaxomicin (6 ng/ml; Fid) and Myxopyronin B (500 ng/ml, MyxB) using antibodies against toxin A (left) and toxin B (right). Per condition, three biological replicates were analyzed. The additional band in the toxin A blot at appr. 150 kDa represents a protein which is unspecifically bound by the primary toxin A antibody. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Additional_file_3_of_Myxopyronin_B_inhibits_growth_of_a_Fidaxomicin-resistant_Clostridioides_difficile_isolate_and_interferes_with_toxin_synthesis/17982112 |
| DOI: |
10.6084/m9.figshare.17982112.v1 |
| الاتاحة: |
https://doi.org/10.6084/m9.figshare.17982112.v1 |
| Rights: |
CC BY + CC0 |
| رقم الانضمام: |
edsbas.22165410 |
| قاعدة البيانات: |
BASE |