Academic Journal
Diagnostic Value of Endoscopic Ultrasound after Neoadjuvant Chemotherapy for Gastric Cancer Restaging: A Meta-Analysis of Diagnostic Test
| العنوان: | Diagnostic Value of Endoscopic Ultrasound after Neoadjuvant Chemotherapy for Gastric Cancer Restaging: A Meta-Analysis of Diagnostic Test |
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| المؤلفون: | Sacerdotianu V. M., Ungureanu B. S., Iordache S., Turcu-Stiolica A., Facciorusso A., Crino S. F., Saftoiu A. |
| المساهمون: | Sacerdotianu, V. M., Ungureanu, B. S., Iordache, S., Turcu-Stiolica, A., Facciorusso, A., Crino, S. F., Saftoiu, A. |
| سنة النشر: | 2022 |
| المجموعة: | Università degli Studi di Foggia: CINECA IRIS Institutional Research Information System |
| مصطلحات موضوعية: | endoscopic ultrasound, Gastric cancer, Restaging |
| الوصف: | This study aimed to evaluate the diagnostic value of endoscopic ultrasound (EUS) after neoadjuvant therapy (NT) for gastric cancer restaging by meta-analysis. We conducted a systematic search of studies published on PubMed and Web of Science up to 30th August 2021. Assessing the risk of bias in the included studies was done with the QUADAS-2 tool. We used R and Review Manager 5.4.1 for calculations and statistical analysis. To evaluate the diagnostic value of EUS after NT for gastric cancer restaging, we performed a meta-analysis on six studies, with a total of 283 patients, including true-positive, true-negative, false-positive, and false-negative results for T1-T4, N0. EUS as a diagnostic test for GC patients after chemotherapy has a relatively low DOR for the T2 (3.96) and T4 stages (4.79) and a relatively high partial AUC for the T2 (0.85) and T4 (0.71) stages. Our results reveal that the pooled sensitivity for T stages after chemotherapy is rather low (29–56%), except for the T3 stage (71%). A potential limitation of our study was the small number of included studies, but no significant heterogeneity was found between them. Our meta-analysis concludes that EUS is not recommended or is still under debate for GC restaging after NT. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/35054266; volume:12; issue:1; firstpage:100; journal:DIAGNOSTICS; http://hdl.handle.net/11369/411943; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85122684696 |
| DOI: | 10.3390/diagnostics12010100 |
| الاتاحة: | http://hdl.handle.net/11369/411943 https://doi.org/10.3390/diagnostics12010100 |
| رقم الانضمام: | edsbas.210F9A3 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/diagnostics12010100 |
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