Academic Journal
The family Picornaviridae currently comprises nine genera
| العنوان: | The family Picornaviridae currently comprises nine genera |
|---|---|
| المؤلفون: | Carl Hay, Paul L. Hallenbeck |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://vir.sgmjournals.org/content/89/5/1265.full.pdf. |
| سنة النشر: | 2008 |
| المجموعة: | CiteSeerX |
| الوصف: | The complete genome sequence of Seneca Valley virus-001 (SVV-001), a small RNA virus, was determined and was shown to have typical picornavirus features. The 7280 nt long genome was predicted to contain a 59 untranslated region (UTR) of 666 nt, followed by a single long open reading frame consisting of 6543 nt, which encodes a 2181 aa polyprotein. This polyprotein could potentially be cleaved into 12 polypeptides in the standard picornavirus L-4-3-4 layout. A 39 UTR of 71 nt was followed by a poly(A) tail of unknown length. Comparisons with other picornaviruses showed that the P1, 2C, 3C and 3D polypeptides of SVV-001 were related most closely to those of the cardioviruses, although they were not related as closely to those of encephalo-myocarditis virus and Theiler’s murine encephalomyelitis virus as the latter were to each other. Most other regions of the polyprotein differed considerably from those of all other known picornaviruses. SVV-001 contains elements of an internal ribosome entry site reminiscent of that found in hepatitis C virus and a number of genetically diverse picornaviruses. SVV-001 is a novel picornavirus and it is proposed that it be classified as the prototype species in a novel genus named ‘Senecavirus’. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.499.5346; http://vir.sgmjournals.org/content/89/5/1265.full.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.499.5346 http://vir.sgmjournals.org/content/89/5/1265.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.210EDC5D |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |