Academic Journal
Essential oils of Moldavian Thymus species: Chemical composition, antioxidant, anti-Aspergillus and antigenotoxic activities
| العنوان: | Essential oils of Moldavian Thymus species: Chemical composition, antioxidant, anti-Aspergillus and antigenotoxic activities |
|---|---|
| المؤلفون: | Aprotosoaie, A., Miron, A., Ciocîrlan, N.G., Ciocarlan, N., Чокырлан, Н.Г., Brebu, M., Roşu, C., Trifan, A., Vochiţa, G., Gherghel, D., Luca, S., Niţă, A., Costache, I., Mihai, C. |
| المصدر: | Flavour and Fragrance Journal 34 (3) 175-186 |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | antigenotoxicity, bioactivity, Chemical composition, essential oils, Thymus species |
| الوصف: | Thymus species are important aromatic, medicinal and culinary plants with a significant economic value. This study evaluated for the first time the chemical composition and in vitro bioactivities of the essential oils EOs from five Moldavian Thymus species T. vulgaris, T. times; citriodorus, T. calcareus and cultivars T. vulgaris lsquo;Faustinirsquo;, T. citriodorus lsquo;Aureusrsquo;. The main compounds in Thymus EOs were: thymol in T. vulgaris and T. calcareus EOs 55.44% and 55.45%, respectively, lavandulol in T. times; citriodorus EO 54.27%, and geraniol in T. citriodorus lsquo;Aureusrsquo; and T. vulgaris lsquo;Faustinirsquo; EOs 60.31% and 31.45%, respectively. T. vulgaris and T. calcareus EOs showed the most potent antioxidant activities EC 50 =0.003 mg/mL in ABTS radical cation scavenging assay and exhibited significant inhibitory effects against aflatoxin-producing Aspergillus flavus fungus MIC=0.25 mu;L/mL. At doses that provided micromolar concentrations of thymol, T. vulgaris and T. calcareus EOs acted genoprotective at preventive and interventional levels against H 2 O 2 -induced genomic damage in V79 cells, the former being more active 6.21% and 5.52% vs. 25.13% and 7.26% tail DNA in pre- and post-treatment protocols, respectively. The genoprotective effects may be ascribed to antioxidant potential and, possibly, to stimulation of DNA repair processes. The Moldavian Thymus species are valuable resources of bioactive EOs for pharmaceutical and food industries T. vulgaris, T.calcareus but also for flavor industry and perfumery T. times; citriodorus, T. citriodorus lsquo;Aureusrsquo;, T. vulgaris lsquo;Faustinirsquo;. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 08825734 |
| Relation: | https://ibn.idsi.md/vizualizare_articol/76170; urn:issn:08825734 |
| DOI: | 10.1002/ffj.3490 |
| الاتاحة: | https://ibn.idsi.md/vizualizare_articol/76170 https://doi.org/10.1002/ffj.3490 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.1EB15A69 |
| قاعدة البيانات: | BASE |
| تدمد: | 08825734 |
|---|---|
| DOI: | 10.1002/ffj.3490 |