Radiosensitivity enhancement effect of combination treatment of PI3K inhibitors and IR in patient-derived cells.

التفاصيل البيبلوغرافية
العنوان: Radiosensitivity enhancement effect of combination treatment of PI3K inhibitors and IR in patient-derived cells.
المؤلفون: Fu-Cheng Chuang (10011345), Chih-Chun Wang (7961687), Jian-Han Chen (3184932), Tzer-Zen Hwang (7961690), Shyh-An Yeh (10011348), Yu-Chieh Su (138988)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, PI 3K inhibitor BYL 719 dose-depend., cell carcinoma, radioresistant OML 1-R cells, mTOR inhibitor AZD 2014, BKM 120, pan-Phosphoinositide 3- kinases, PI 3k inhibitors, radiation therapy failure, combination treatment, BYL 719, HNSCC, patient-derived OSCC cells, PI 3K inhibitor BKM 120, OSCC cells
الوصف: Patient-derived cells were derived from patients with OSCC. The cells were pretreated with BKM120 or BYL719 at 2 μM and then irradiated at 0 or 4 Gy. After 14 days, colonies were stained with crystal violet and quantified by an ELISA reader. Typical images of colony growth for the different treatments are shown. *P < 0.01 compared with the control group.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Radiosensitivity_enhancement_effect_of_combination_treatment_of_PI3K_inhibitors_and_IR_in_patient-derived_cells_/13617312
DOI: 10.1371/journal.pone.0245715.g004
الاتاحة: https://doi.org/10.1371/journal.pone.0245715.g004
Rights: CC BY 4.0
رقم الانضمام: edsbas.1E4584FB
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pone.0245715.g004