Academic Journal
Diversity in EWAS: current state, challenges, and solutions
العنوان: | Diversity in EWAS: current state, challenges, and solutions |
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المؤلفون: | Breeze, Charles E., Wong, Jason Y. Y., Beck, Stephan, Berndt, Sonja I., Franceschini, Nora |
المساهمون: | Division of Cancer Epidemiology and Genetics, National Cancer Institute |
المصدر: | Genome Medicine ; volume 14, issue 1 ; ISSN 1756-994X |
بيانات النشر: | Springer Science and Business Media LLC |
سنة النشر: | 2022 |
الوصف: | Here, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and DNAm research in diverse populations. The strategies we propose include fostering community involvement, new data generation, and cost-effective approaches such as locus-specific analysis and ancestry variable region analysis. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1186/s13073-022-01065-3 |
DOI: | 10.1186/s13073-022-01065-3.pdf |
DOI: | 10.1186/s13073-022-01065-3/fulltext.html |
الاتاحة: | http://dx.doi.org/10.1186/s13073-022-01065-3 https://link.springer.com/content/pdf/10.1186/s13073-022-01065-3.pdf https://link.springer.com/article/10.1186/s13073-022-01065-3/fulltext.html |
Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
رقم الانضمام: | edsbas.1CFAEAE4 |
قاعدة البيانات: | BASE |
DOI: | 10.1186/s13073-022-01065-3 |
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