التفاصيل البيبلوغرافية
| العنوان: |
Multivalvular Endocarditis: A Rare Condition with Poor Prognosis. |
| المؤلفون: |
Álvarez Zaballos, Sara, González-Ramallo, Víctor, Quintana, Eduard, Muñoz, Patricia, De la Villa, Sofía, Fariñas, Maria Carmen, Arnáiz de las Revillas, Francisco, Alarcón, Aristides de, Rodríguez-Esteban, M. Ángeles, Miró Meda, José M., Goenaga Sánchez, Miguel Ángel, Goikoetxea Agirre, Ane Josune, García Vázquez, Elisa, Boix Palop, Lucía, Martínez-Sellés, Manue, Grupo de Apoyo al Manejo de la Endocarditis infecc |
| المصدر: |
Articles publicats en revistes (Medicina) |
| بيانات النشر: |
MDPI |
| سنة النشر: |
2022 |
| المجموعة: |
Dipòsit Digital de la Universitat de Barcelona |
| مصطلحات موضوعية: |
Endocarditis, Pronòstic mèdic, Vàlvules cardíaques, Mortalitat, Prognosis, Heart valves, Mortality |
| الوصف: |
Background. Infective endocarditis (IE) is a severe condition. Our aim was to describe the profile and prognosis of patients with multivalvular infective endocarditis (MIE) and compare them to single-valve IE (SIE). Methods. We used a retrospective analysis of the Spanish IE Registry (2008−2020). Results. From 4064 definite cases of valvular IE, 577 (14.2%) had MIE. In patients with MIE, the most common locations were mitral (552, 95.7%) and aortic (550, 95.3%), with mitral-aortic involvement present in 507 patients (87.9%). The most common etiologies were S. viridans (192, 33.3%) and S. aureus (113, 19.6%). MIE involved only native valves in 450 patients (78.0%). Compared with patients with SIE, patients with MIE had a similar age (69 vs. 67 years, respectively, p = 0.27) and similar baseline characteristics, but were more frequently men (67.1% vs. 72.9%, p = 0.005) and had a higher incidence of intracardiac complications (36.2% vs. 50.4%, p < 0.001), heart failure (42.7% vs. 52.9%, p < 0.001), surgical indication (67.7 vs. 85.1%, p < 0.001), surgery (46.3% vs. 56.3%), and in-hospital mortality (26.9% vs. 34.3%, p < 0.001). MIE was an independent predictor of in-hospital mortality (odds ratio (OR) 1.3, 95% confidence interval (CI) 1.1−1.7, p = 0.004) but did not have an independent association with 1-year mortality (OR 1.1, 95% CI 0.9−1.4, p = 0.43). Conclusions. About one-seventh of the valvular IE patients had MIE, mainly due to mitral-aortic involvement. MIE is associated with a poor in-hospital prognosis. An early diagnosis and treatment of IE might avoid its spread to a second valve. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
10 p.; application/pdf |
| اللغة: |
English |
| تدمد: |
2077-0383 |
| Relation: |
Reproducció del document publicat a: https://doi.org/10.3390/jcm11164736; Journal of Clinical Medicine, 2022, vol. 11, num. 16, p. 4736; https://doi.org/10.3390/jcm11164736; http://hdl.handle.net/2445/202163; 729634; 9329163 |
| الاتاحة: |
http://hdl.handle.net/2445/202163 |
| Rights: |
cc-by (c) Álvarez Zaballos, Sara et al., 2022 ; https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.1C5FF2E9 |
| قاعدة البيانات: |
BASE |
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