Outcomes following repair of anomalous coronary artery from the pulmonary artery in infants: results from a procedure-based national database

التفاصيل البيبلوغرافية
العنوان:	Outcomes following repair of anomalous coronary artery from the pulmonary artery in infants: results from a procedure-based national database
المؤلفون:	Fudulu, DP, Dorobantu, DM, Azar Sharabiani, MT, Angelini, GD, Caputo, M, Parry, AJ, Stoica, SC
بيانات النشر:	BMJ Publishing Group
سنة النشر:	2015
المجموعة:	Imperial College London: Spiral
مصطلحات موضوعية:	CONGENITAL HEART DISEASE, QUALITY OF CARE AND OUTCOMES
الوصف:	BACKGROUND: Anomalous coronary artery from the pulmonary artery (ACAPA) is a very rare congenital anomaly that often occurs during infancy. Patients can present in a critical condition. METHODS: We analysed procedure-related data from a national audit database for the period 2000-2013. RESULTS: A total of 120 patients <1 year had repair of isolated ACAPA using a coronary transfer or the tunnel (Takeuchi) operation. Seven patients (6.8%) required a mitral valve procedure at index and eight patients (7.8%) had a mitral valve repair/replacement during follow-up, including mitral reoperations. Follow-up data (>30 days) were available in 102 patients and the mean follow-up time was 4.7 years. The 30-day overall mortality was 1.9%, higher for neonates (16.7% vs 1%, p=0.1) and after postoperative extracorporeal membrane oxygenation (ECMO) (20% vs 1%, p=0.09). At 10 years the survival estimate is 95.1%, freedom from coronary and mitral reintervention being 95.9% and 91.2%, respectively. Use of postoperative ECMO was a risk factor for long-term mortality (p<0.001). Risk factors for coronary reintervention were age under 30 days (p=0.06) and the need for postoperative ECMO (p=0.02). Age under 30 days (p=0.002) was a risk factor for mitral reintervention. CONCLUSIONS: To our knowledge this is the largest series to date. These preliminary national results show that early outcomes are good and medium-term attrition acceptable. Poor outcomes are correlated with early presentation, also with the need for postoperative circulatory support.
نوع الوثيقة:	article in journal/newspaper
اللغة:	unknown
تدمد:	2053-3624
Relation:	Open Heart; http://hdl.handle.net/10044/1/41497; http://dx.doi.org/10.1136/openhrt-2015-000277
DOI:	10.1136/openhrt-2015-000277
الاتاحة:	http://hdl.handle.net/10044/1/41497 https://doi.org/10.1136/openhrt-2015-000277
Rights:	This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
رقم الانضمام:	edsbas.1C0301E5
قاعدة البيانات:	BASE

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الوصف
تدمد:	20533624
DOI:	10.1136/openhrt-2015-000277