Academic Journal
In vitro approach to evaluate the fermentation pattern of inulin-rich food in obese individuals.
| العنوان: | In vitro approach to evaluate the fermentation pattern of inulin-rich food in obese individuals. |
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| المؤلفون: | Kalala, Gaétan, Kambashi, Bienvenu, Taminiau, Bernard, Schroyen, Martine, Everaert, Nadia, Beckers, Yves, Richel, Aurore, Njeumen, Patrick, Pachikian, Barbara D., Neyrinck, Audrey M., Hiel, Sophie, Rodriguez, Julie, Fall, Papa A, Daube, Georges, Thissen, Jean-Paul, Delzenne, Nathalie M., Bindelle, Jérôme |
| المساهمون: | UCL - SSS/LDRI - Louvain Drug Research Institute, UCL - SSS/IONS - Institute of NeuroScience, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - (SLuc) Service d'endocrinologie et de nutrition |
| المصدر: | The British journal of nutrition, Vol. 123, no. 4, p. 472-479 (2020) |
| بيانات النشر: | Cambridge University Press |
| سنة النشر: | 2020 |
| المجموعة: | DIAL@USL-B (Université Saint-Louis, Bruxelles) |
| مصطلحات موضوعية: | In vitro fermentation, Fibre residues, Inulin, Obese |
| الوصف: | Alterations of the gut microbiome have been associated with obesity and metabolic disorders. The gut microbiota can be influenced by the intake of dietary fibres with prebiotic properties, such as inulin-type fructans. This study tested the hypothesis that obese individuals subjected for 12 weeks to a inulin-enriched versus inulin-poor diet have differential faecal fermentation patterns. The fermentation of cellulose and inulin hydrolysates, of six different inulin-rich and inulin-poor vegetables of both groups was analysed in vitro on faecal inocula. The results showed that the microbiota from obese patients who received fructan-rich diet for three weeks produce more gas and total short-chain fatty acid (SCFA) compared to the microbiota taken of the same individuals before the treatment. Obese individuals fed with a low-fructan diet produce less gas and less SCFA compared to the treated group. This study highlighted profound changes in microbiota fermentation capacity obtained by prebiotic intervention in obese individuals, which favors the production of specific bioactive metabolites. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0007-1145 1475-2662 |
| Relation: | boreal:224072; http://hdl.handle.net/2078.1/224072; info:pmid/31724526; urn:ISSN:0007-1145; urn:EISSN:1475-2662 |
| DOI: | 10.1017/S0007114519002915 |
| الاتاحة: | http://hdl.handle.net/2078.1/224072 https://doi.org/10.1017/S0007114519002915 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.1BD159C2 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00071145 14752662 |
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| DOI: | 10.1017/S0007114519002915 |