Academic Journal
Genotyping of Toxoplasma gondii in a lethal toxoplasmosis outbreak affecting captive howler monkeys ( Alouatta sp.)
| العنوان: | Genotyping of Toxoplasma gondii in a lethal toxoplasmosis outbreak affecting captive howler monkeys ( Alouatta sp.) |
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| المؤلفون: | Santana, Clarissa Helena, de Oliveira, Ayisa Rodrigues, dos Santos, Daniel O., Pimentel, Samantha Pinheiro, de Souza, Lucas dos Reis, Moreira, Larissa Giannini Alves, Braz, Heloísia Maria Bressan, de Carvalho, Thaynara Parente, Lopes, Carlos Eduardo Bastos, Oliveira, Jefferson Bruno Soares, de Paula, Nayara Ferreira, de Carvalho, Marcelo Pires Nogueira, Alves, Bruna Farias, Pena, Hilda Fátima Jesus, Santos, Renato Lima |
| المساهمون: | Fundação de Amparo à Pesquisa do Estado de Minas Gerais, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico |
| المصدر: | Journal of Medical Primatology ; volume 50, issue 2, page 99-107 ; ISSN 0047-2565 1600-0684 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2020 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Background Toxoplasmosis is a zoonotic disease that affects humans and warm‐blooded animals. This study describes an outbreak of toxoplasmosis in howler monkeys ( Alouatta sp.) and survival of capuchins ( Sapajus apella ), under the same environmental conditions. Methods Howler monkeys were submitted to post‐mortem examination. Tissue samples were processed to histopathology and immunohistochemistry to detect lesions and tachyzoites of Toxoplasma gondii . Tissue samples were also frozen and submitted to PCR and genotyping of T. gondii . Results Typical lesions were observed in several organs including the liver, lymph node, and brain, with intralesional cysts and tachyzoites of T. gondii demonstrated by immunohistochemistry. T. gondii genomic sequences were amplified by PCR, and genotyping characterized the same T. gondii clone in all howler monkeys. Conclusions Our results support the notion that some species of neotropical primates are highly susceptible to toxoplasmosis and the hypothesis that capuchins ( S. apella ) may be resistant. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/jmp.12506 |
| الاتاحة: | http://dx.doi.org/10.1111/jmp.12506 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jmp.12506 https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jmp.12506 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.1BC4715E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/jmp.12506 |
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