التفاصيل البيبلوغرافية
| العنوان: |
Prolonged CDK4/6 inhibition response of gene expression and splicing in A375 and CHL1. |
| المؤلفون: |
Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E. Sheppard, David L. Goode |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Developmental Biology, Marine Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising new treatments, length mrna sequencing, important downstream component, 6 inhibitor resistance, 6 inhibitor palbociclib, gene expression profiles, prmt5 inhibitor gsk3326595, findings indicate cdk4, dependent kinases 4, regulate alternative splicing, mrna splicing induced, differential gene expression, 6 inhibition result, although prmt5 inhibition, melanoma , gene expression, alternative splicing |
| الوصف: |
PCA plot of CDK4/6 inhibited samples showing clusters between replicates in (A) A375 and (B) CHL1 cell. (C) Number of upregulated and downregulated genes in CDK4/6 inhibited samples in A375 (left) and CHL1 (right) cell. (D) Number of differentially spliced events in CDK4/6 inhibited samples in A375 (left) and CHL1 (right) cell. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Prolonged_CDK4_6_inhibition_response_of_gene_expression_and_splicing_in_A375_and_CHL1_/24489866 |
| DOI: |
10.1371/journal.pone.0292278.g001 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0292278.g001
https://figshare.com/articles/figure/Prolonged_CDK4_6_inhibition_response_of_gene_expression_and_splicing_in_A375_and_CHL1_/24489866 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.1B4990A2 |
| قاعدة البيانات: |
BASE |