Academic Journal
Diphenylacetylene-linked peptide strands induce bidirectional β-sheet formation.
| العنوان: | Diphenylacetylene-linked peptide strands induce bidirectional β-sheet formation. |
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| المؤلفون: | Lingard, H, Han, J, Thompson, A, Leung, I, Scott, RT, Thompson, S, Hamilton, A |
| بيانات النشر: | Wiley |
| سنة النشر: | 2016 |
| المجموعة: | Oxford University Research Archive (ORA) |
| الوصف: | In the search for synthetic mimics of protein secondary structures relevant to the mediation of protein-protein interactions, we have synthesized a series of tetrasubstituted diphenylacetylenes that display β-sheet structures in two directions. Extensive X-ray crystallographic and NMR solution phase studies are consistent with these proteomimetics adopting sheet structures, displaying both hydrophobic and hydrophilic amino acid side chains. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://ora.ox.ac.uk/objects/uuid:a70df071-0881-440f-b8d5-519faac07a72; https://doi.org/10.1002/anie.201309353 |
| DOI: | 10.1002/anie.201309353 |
| الاتاحة: | https://doi.org/10.1002/anie.201309353 https://ora.ox.ac.uk/objects/uuid:a70df071-0881-440f-b8d5-519faac07a72 |
| Rights: | info:eu-repo/semantics/embargoedAccess |
| رقم الانضمام: | edsbas.1B1B8F6B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/anie.201309353 |
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